Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.

Linn Gillberg; Alexander Perfilyev; Charlotte Brøns; Martin Thomasen; Louise G Grunnet; Petr Volkov; Fredrik Rosqvist; David Iggman; Ingrid Dahlman; Ulf Risérus; Tina Rönn; Emma A Nilsson; Allan Vaag; Charlotte Ling

doi:10.1007/s00125-015-3852-9

Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.

Linn Gillberg, Alexander Perfilyev, Charlotte Brøns, Martin Thomasen, Louise G Grunnet, Petr Volkov, Fredrik Rosqvist, David Iggman, Ingrid Dahlman, Ulf Risérus, Tina Rönn, Emma A Nilsson, Allan Vaag, Charlotte Ling

Research output: Contribution to journal › Article › peer-review

Abstract

Individuals who had a low birthweight (LBW) are at an increased risk of insulin resistance and type 2 diabetes when exposed to high-fat overfeeding (HFO). We studied genome-wide mRNA expression and DNA methylation in subcutaneous adipose tissue (SAT) after 5 days of HFO and after a control diet in 40 young men, of whom 16 had LBW.

Original language	English
Pages (from-to)	799-812
Journal	Diabetologia
Volume	59
Issue number	4
Early online date	2016 Jan 11
DOIs	https://doi.org/10.1007/s00125-015-3852-9
Publication status	Published - 2016

Subject classification (UKÄ)

Endocrinology and Diabetes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s00125-015-3852-9

http://www.ncbi.nlm.nih.gov/pubmed/26750116?dopt=Abstract

1 Doctoral Thesis (compilation)

DNA methylation patterns in human adipose tissue in relation to diet and type 2 diabetes
Perfilyev, A., 2018, Lund: Lund University: Faculty of Medicine. 47 p.
Research output: Thesis › Doctoral Thesis (compilation)

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Gillberg, L., Perfilyev, A., Brøns, C., Thomasen, M., Grunnet, L. G., Volkov, P., Rosqvist, F., Iggman, D., Dahlman, I., Risérus, U., Rönn, T., Nilsson, E. A., Vaag, A., & Ling, C. (2016). Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding. Diabetologia, 59(4), 799-812. https://doi.org/10.1007/s00125-015-3852-9

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title = "Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.",

abstract = "Individuals who had a low birthweight (LBW) are at an increased risk of insulin resistance and type 2 diabetes when exposed to high-fat overfeeding (HFO). We studied genome-wide mRNA expression and DNA methylation in subcutaneous adipose tissue (SAT) after 5 days of HFO and after a control diet in 40 young men, of whom 16 had LBW.",

author = "Linn Gillberg and Alexander Perfilyev and Charlotte Br{\o}ns and Martin Thomasen and Grunnet, {Louise G} and Petr Volkov and Fredrik Rosqvist and David Iggman and Ingrid Dahlman and Ulf Ris{\'e}rus and Tina R{\"o}nn and Nilsson, {Emma A} and Allan Vaag and Charlotte Ling",

year = "2016",

doi = "10.1007/s00125-015-3852-9",

language = "English",

volume = "59",

pages = "799--812",

journal = "Diabetologia",

issn = "1432-0428",

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Gillberg, L, Perfilyev, A, Brøns, C, Thomasen, M, Grunnet, LG, Volkov, P, Rosqvist, F, Iggman, D, Dahlman, I, Risérus, U, Rönn, T, Nilsson, EA, Vaag, A & Ling, C 2016, 'Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.', Diabetologia, vol. 59, no. 4, pp. 799-812. https://doi.org/10.1007/s00125-015-3852-9

TY - JOUR

T1 - Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.

AU - Gillberg, Linn

AU - Perfilyev, Alexander

AU - Brøns, Charlotte

AU - Thomasen, Martin

AU - Grunnet, Louise G

AU - Volkov, Petr

AU - Rosqvist, Fredrik

AU - Iggman, David

AU - Dahlman, Ingrid

AU - Risérus, Ulf

AU - Rönn, Tina

AU - Nilsson, Emma A

AU - Vaag, Allan

AU - Ling, Charlotte

PY - 2016

Y1 - 2016

N2 - Individuals who had a low birthweight (LBW) are at an increased risk of insulin resistance and type 2 diabetes when exposed to high-fat overfeeding (HFO). We studied genome-wide mRNA expression and DNA methylation in subcutaneous adipose tissue (SAT) after 5 days of HFO and after a control diet in 40 young men, of whom 16 had LBW.

AB - Individuals who had a low birthweight (LBW) are at an increased risk of insulin resistance and type 2 diabetes when exposed to high-fat overfeeding (HFO). We studied genome-wide mRNA expression and DNA methylation in subcutaneous adipose tissue (SAT) after 5 days of HFO and after a control diet in 40 young men, of whom 16 had LBW.

U2 - 10.1007/s00125-015-3852-9

DO - 10.1007/s00125-015-3852-9

M3 - Article

C2 - 26750116

SN - 1432-0428

VL - 59

SP - 799

EP - 812

JO - Diabetologia

JF - Diabetologia

IS - 4

ER -

Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.

Abstract

Subject classification (UKÄ)

UN SDGs

Access to Document

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Research output

DNA methylation patterns in human adipose tissue in relation to diet and type 2 diabetes

Cite this