Adrenoleukodystrophy--unusual CT and MR findings in two siblings. Case reports

P C Sundgren; Gösta Blennow; Elisabet Englund; Stig Holtås

Adrenoleukodystrophy--unusual CT and MR findings in two siblings. Case reports

P C Sundgren, Gösta Blennow, Elisabet Englund, Stig Holtås

Research output: Contribution to journal › Article › peer-review

Abstract

PURPOSE: To describe the unusual appearance of adrenoleukodystrophy (ALD) in MR imaging. MATERIAL AND METHODS: An analysis was made of MR findings, histopathology and clinical course in the cases of two brothers with ALD. RESULTS: The older brother presented with frontal contrast-enhanced lesions, including a cyst. These were initially misinterpreted as a tumour at both radiology and pathology. The correct diagnosis was made after the discovery of very-long-chain fatty acids in the blood. The younger brother presented initially with involvement of various segments of the corticospinal tract. CONCLUSION: It is important that the radiologist be aware of the variants of ALD in MR imaging so as to avoid diagnostic mistakes.

Original language	English
Pages (from-to)	77-80
Journal	Acta Radiologica
Volume	39
Issue number	1
Publication status	Published - 1998

Bibliographical note

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Paediatrics (Lund) (013002000), Pathology, (Lund) (013030000), Diagnostic Radiology, (Lund) (013038000)

Subject classification (UKÄ)

Radiology and Medical Imaging

Cite this

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title = "Adrenoleukodystrophy--unusual CT and MR findings in two siblings. Case reports",

abstract = "PURPOSE: To describe the unusual appearance of adrenoleukodystrophy (ALD) in MR imaging. MATERIAL AND METHODS: An analysis was made of MR findings, histopathology and clinical course in the cases of two brothers with ALD. RESULTS: The older brother presented with frontal contrast-enhanced lesions, including a cyst. These were initially misinterpreted as a tumour at both radiology and pathology. The correct diagnosis was made after the discovery of very-long-chain fatty acids in the blood. The younger brother presented initially with involvement of various segments of the corticospinal tract. CONCLUSION: It is important that the radiologist be aware of the variants of ALD in MR imaging so as to avoid diagnostic mistakes.",

author = "Sundgren, {P C} and G{\"o}sta Blennow and Elisabet Englund and Stig Holt{\aa}s",

note = "The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Paediatrics (Lund) (013002000), Pathology, (Lund) (013030000), Diagnostic Radiology, (Lund) (013038000)",

year = "1998",

language = "English",

volume = "39",

pages = "77--80",

journal = "Acta Radiologica",

issn = "1600-0455",

publisher = "SAGE Publications",

number = "1",

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TY - JOUR

T1 - Adrenoleukodystrophy--unusual CT and MR findings in two siblings. Case reports

AU - Sundgren, P C

AU - Blennow, Gösta

AU - Englund, Elisabet

AU - Holtås, Stig

N1 - The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Paediatrics (Lund) (013002000), Pathology, (Lund) (013030000), Diagnostic Radiology, (Lund) (013038000)

PY - 1998

Y1 - 1998

N2 - PURPOSE: To describe the unusual appearance of adrenoleukodystrophy (ALD) in MR imaging. MATERIAL AND METHODS: An analysis was made of MR findings, histopathology and clinical course in the cases of two brothers with ALD. RESULTS: The older brother presented with frontal contrast-enhanced lesions, including a cyst. These were initially misinterpreted as a tumour at both radiology and pathology. The correct diagnosis was made after the discovery of very-long-chain fatty acids in the blood. The younger brother presented initially with involvement of various segments of the corticospinal tract. CONCLUSION: It is important that the radiologist be aware of the variants of ALD in MR imaging so as to avoid diagnostic mistakes.

AB - PURPOSE: To describe the unusual appearance of adrenoleukodystrophy (ALD) in MR imaging. MATERIAL AND METHODS: An analysis was made of MR findings, histopathology and clinical course in the cases of two brothers with ALD. RESULTS: The older brother presented with frontal contrast-enhanced lesions, including a cyst. These were initially misinterpreted as a tumour at both radiology and pathology. The correct diagnosis was made after the discovery of very-long-chain fatty acids in the blood. The younger brother presented initially with involvement of various segments of the corticospinal tract. CONCLUSION: It is important that the radiologist be aware of the variants of ALD in MR imaging so as to avoid diagnostic mistakes.

M3 - Article

SN - 1600-0455

VL - 39

SP - 77

EP - 80

JO - Acta Radiologica

JF - Acta Radiologica

IS - 1

ER -

Adrenoleukodystrophy--unusual CT and MR findings in two siblings. Case reports

Abstract

Bibliographical note

Subject classification (UKÄ)

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