Adsorption of the intrinsically disordered saliva protein histatin 5 to silica surfaces. A Monte Carlo simulation and ellipsometry study.

Kristin Hyltegren; Tommy Nylander; Mikael Lund; Marie Skepö

doi:10.1016/j.jcis.2016.01.025

Adsorption of the intrinsically disordered saliva protein histatin 5 to silica surfaces. A Monte Carlo simulation and ellipsometry study.

Kristin Hyltegren, Tommy Nylander, Mikael Lund, Marie Skepö

Research output: Contribution to journal › Article › peer-review

Abstract

The adsorption of histatin 5 to hydrophilic silica surfaces is governed by electrostatic attractive forces between the positive protein and the negative surface. Hence pH and ionic strength control the adsorbed amount, which can be described by coarse-grained Monte Carlo simulations accounting for electrostatic forces and charge regulation of the protein.

Original language	English
Pages (from-to)	280-290
Journal	Journal of Colloid and Interface Science
Volume	467
DOIs	https://doi.org/10.1016/j.jcis.2016.01.025
Publication status	Published - 2016

Subject classification (UKÄ)

Physical Chemistry (including Surface- and Colloid Chemistry)

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10.1016/j.jcis.2016.01.025

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title = "Adsorption of the intrinsically disordered saliva protein histatin 5 to silica surfaces. A Monte Carlo simulation and ellipsometry study.",

abstract = "The adsorption of histatin 5 to hydrophilic silica surfaces is governed by electrostatic attractive forces between the positive protein and the negative surface. Hence pH and ionic strength control the adsorbed amount, which can be described by coarse-grained Monte Carlo simulations accounting for electrostatic forces and charge regulation of the protein.",

author = "Kristin Hyltegren and Tommy Nylander and Mikael Lund and Marie Skep{\"o}",

year = "2016",

doi = "10.1016/j.jcis.2016.01.025",

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AU - Hyltegren, Kristin

AU - Nylander, Tommy

AU - Lund, Mikael

AU - Skepö, Marie

PY - 2016

Y1 - 2016

N2 - The adsorption of histatin 5 to hydrophilic silica surfaces is governed by electrostatic attractive forces between the positive protein and the negative surface. Hence pH and ionic strength control the adsorbed amount, which can be described by coarse-grained Monte Carlo simulations accounting for electrostatic forces and charge regulation of the protein.

AB - The adsorption of histatin 5 to hydrophilic silica surfaces is governed by electrostatic attractive forces between the positive protein and the negative surface. Hence pH and ionic strength control the adsorbed amount, which can be described by coarse-grained Monte Carlo simulations accounting for electrostatic forces and charge regulation of the protein.

UR - https://www.scopus.com/pages/publications/84955451839

U2 - 10.1016/j.jcis.2016.01.025

DO - 10.1016/j.jcis.2016.01.025

M3 - Article

C2 - 26809106

SN - 1095-7103

VL - 467

SP - 280

EP - 290

JO - Journal of Colloid and Interface Science

JF - Journal of Colloid and Interface Science

ER -

Adsorption of the intrinsically disordered saliva protein histatin 5 to silica surfaces. A Monte Carlo simulation and ellipsometry study.

Abstract

Subject classification (UKÄ)

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Coarse-Grained Modelling of Protein Adsorption

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