Advances in Sepsis Research.

Peter Bentzer; James A Russell; Keith R Walley

doi:10.1016/j.ccm.2015.05.009

Advances in Sepsis Research.

Peter Bentzer, James A Russell, Keith R Walley

Anesthesiology and Intensive Care

University of British Columbia

Research output: Contribution to journal › Review article › peer-review

Abstract

Recent research has identified promising targets for therapeutic interventions aimed at modulating the inflammatory response in sepsis. Herein, the authors describe mechanisms involved in the clearance of pathogen toxin from the circulation and potential interventions aimed at enhancing clearance mechanisms. The authors also describe advances in the understanding of the innate immune response as potential therapeutic targets. Finally, novel potential treatment strategies aimed at decreasing vascular leak are discussed.

Original language	English
Pages (from-to)	521-530
Journal	Clinics in Chest Medicine
Volume	36
Issue number	3
DOIs	https://doi.org/10.1016/j.ccm.2015.05.009
Publication status	Published - 2015

Subject classification (UKÄ)

Anesthesiology and Intensive Care

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10.1016/j.ccm.2015.05.009

http://www.ncbi.nlm.nih.gov/pubmed/26304288?dopt=Abstract

Cite this

@article{f16d33fc59c84dd295e1239f9358d085,

title = "Advances in Sepsis Research.",

abstract = "Recent research has identified promising targets for therapeutic interventions aimed at modulating the inflammatory response in sepsis. Herein, the authors describe mechanisms involved in the clearance of pathogen toxin from the circulation and potential interventions aimed at enhancing clearance mechanisms. The authors also describe advances in the understanding of the innate immune response as potential therapeutic targets. Finally, novel potential treatment strategies aimed at decreasing vascular leak are discussed.",

author = "Peter Bentzer and Russell, {James A} and Walley, {Keith R}",

year = "2015",

doi = "10.1016/j.ccm.2015.05.009",

language = "English",

volume = "36",

pages = "521--530",

journal = "Clinics in Chest Medicine",

issn = "1557-8216",

publisher = "Elsevier",

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T1 - Advances in Sepsis Research.

AU - Bentzer, Peter

AU - Russell, James A

AU - Walley, Keith R

PY - 2015

Y1 - 2015

N2 - Recent research has identified promising targets for therapeutic interventions aimed at modulating the inflammatory response in sepsis. Herein, the authors describe mechanisms involved in the clearance of pathogen toxin from the circulation and potential interventions aimed at enhancing clearance mechanisms. The authors also describe advances in the understanding of the innate immune response as potential therapeutic targets. Finally, novel potential treatment strategies aimed at decreasing vascular leak are discussed.

AB - Recent research has identified promising targets for therapeutic interventions aimed at modulating the inflammatory response in sepsis. Herein, the authors describe mechanisms involved in the clearance of pathogen toxin from the circulation and potential interventions aimed at enhancing clearance mechanisms. The authors also describe advances in the understanding of the innate immune response as potential therapeutic targets. Finally, novel potential treatment strategies aimed at decreasing vascular leak are discussed.

U2 - 10.1016/j.ccm.2015.05.009

DO - 10.1016/j.ccm.2015.05.009

M3 - Review article

C2 - 26304288

SN - 1557-8216

VL - 36

SP - 521

EP - 530

JO - Clinics in Chest Medicine

JF - Clinics in Chest Medicine

IS - 3

ER -

Advances in Sepsis Research.

Abstract

Subject classification (UKÄ)

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Cite this