An esterolytic imprinted polymer prepared via a silica-supported transition state analogue

K Lettau, A Warsinke, A Laschewsky, Klaus Mosbach, Ecevit Yilmaz, F W Scheller

Research output: Contribution to journalArticlepeer-review

Abstract

In this work we describe a new preparation method for an esterolytic imprinted polymer with catalytic sites on the surface. A template was prepared by immobilizing a transition state analogue (phosphoramidic acid derivative) of an esterolytic reaction within porous silica particles. Polymerization within the pores was carried out using 4-vinylimidazole as a functional monomer and divinylbenzene as a cross-linker. The polymer was released by dissolution of the silica support with hydrofluoric acid and catalytic properties were studied by incubation with three different 4-nitrophenylesters and spectrophotometric determination of the released 4-nitrophenol. For 4-nitrophenyl acetate an activity of 211 nmol min(-1) mg(-1) and a K-m value of 2.2 mmol L-1 was obtained.
Original languageEnglish
Pages (from-to)2745-2749
JournalChemistry of Materials
Volume16
Issue number14
DOIs
Publication statusPublished - 2004

Subject classification (UKÄ)

  • Materials Chemistry

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