Analysis and quantification of parabens in cosmetic products by utilizing hollow fibre-supported liquid membrane and high performance liquid chromatography with ultraviolet detection

Titus A M Msagati, Thaer Barri, Niklas Larsson, Jan Åke Jönsson

Research output: Contribution to journalArticlepeer-review

Abstract

A simple and direct method based on hollow fibresupported
liquid membrane (HFSLM) extraction
and liquid chromatography equipped with a UV
detector was developed for analysis and quantification
of parabens in cosmetic products. The parabens
analysed included methyl, ethyl, propyl,
isobutyl and butyl paraben. The HFSLM extraction
was carried out by employing di-n-hexyl ether as
organic liquid that was immobilized in the hollow
fibre membrane. The HFSLM extraction is simple,
cheap, minimizes the use of solvents and uses disposable
material. In an investigation of 11 paraben-
containing cosmetic products, the levels of
parabens (sum of all parabens in a product) ranged
from 0.43% to 0.79% (w/w) for skin care
products, 0.07–0.44% for hair fixing gels and
0.30–0.52% for soap solutions. The levels of individual
parabens in individual cosmetic products
ranged between 0.03% and 0.42% w/w for skin
care products, 0.07% and 0.26% w/w for hair fixing
gels and between 0.11% and 0.34% w/w for
soap solutions. Parabens were found in the highest
concentrations in skin care products followed by
soap solutions and the least amounts were found
in hair fixing gels. Of the paraben-containing products
tested, all of them contained methyl paraben
and about 90% contained propyl paraben in addition
to methyl paraben. One product contained all
the parabens analysed.
Original languageEnglish
Pages (from-to)297-307
JournalInternational Journal of Cosmetic Science
Volume30
Issue number4
DOIs
Publication statusPublished - 2008

Bibliographical note

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Analytical Chemistry (S/LTH) (011001004)

Subject classification (UKÄ)

  • Analytical Chemistry

Free keywords

  • Cosmetics
  • parabens
  • hollow fibre-supported liquid membrane
  • high performance liquid chromatography

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