Anticitrullinated protein antibodies and rheumatoid factor are associated with increased mortality but with different causes of death in patients with rheumatoid arthritis: a longitudinal study in three European cohorts.

S Ajeganova; J H Humphreys; M K Verheul; H W van Steenbergen; J A B van Nies; I Hafström; Björn Svensson; T W J Huizinga; L A Trouw; S M M Verstappen; A H M van der Helm-van Mil

doi:10.1136/annrheumdis-2015-208579

Anticitrullinated protein antibodies and rheumatoid factor are associated with increased mortality but with different causes of death in patients with rheumatoid arthritis: a longitudinal study in three European cohorts.

S Ajeganova, J H Humphreys, M K Verheul, H W van Steenbergen, J A B van Nies, I Hafström, Björn Svensson, T W J Huizinga, L A Trouw, S M M Verstappen, A H M van der Helm-van Mil

Rheumatology

Research output: Contribution to journal › Article › peer-review

Abstract

Patients with rheumatoid arthritis (RA)-related autoantibodies have an increased mortality rate. Different autoantibodies are frequently co-occurring and it is unclear which autoantibodies associate with increased mortality. In addition, association with different causes of death is thus far unexplored. Both questions were addressed in three early RA populations.

Original language	English
Journal	Annals of the Rheumatic Diseases
Early online date	2016 Jan 12
DOIs	https://doi.org/10.1136/annrheumdis-2015-208579
Publication status	Published - 2016

Subject classification (UKÄ)

Clinical Medicine

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10.1136/annrheumdis-2015-208579

http://www.ncbi.nlm.nih.gov/pubmed/26757747?dopt=Abstract

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Ajeganova, S., Humphreys, J. H., Verheul, M. K., van Steenbergen, H. W., van Nies, J. A. B., Hafström, I., Svensson, B., Huizinga, T. W. J., Trouw, L. A., Verstappen, S. M. M., & van der Helm-van Mil, A. H. M. (2016). Anticitrullinated protein antibodies and rheumatoid factor are associated with increased mortality but with different causes of death in patients with rheumatoid arthritis: a longitudinal study in three European cohorts. Annals of the Rheumatic Diseases. https://doi.org/10.1136/annrheumdis-2015-208579

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title = "Anticitrullinated protein antibodies and rheumatoid factor are associated with increased mortality but with different causes of death in patients with rheumatoid arthritis: a longitudinal study in three European cohorts.",

abstract = "Patients with rheumatoid arthritis (RA)-related autoantibodies have an increased mortality rate. Different autoantibodies are frequently co-occurring and it is unclear which autoantibodies associate with increased mortality. In addition, association with different causes of death is thus far unexplored. Both questions were addressed in three early RA populations.",

author = "S Ajeganova and Humphreys, {J H} and Verheul, {M K} and {van Steenbergen}, {H W} and {van Nies}, {J A B} and I Hafstr{\"o}m and Bj{\"o}rn Svensson and Huizinga, {T W J} and Trouw, {L A} and Verstappen, {S M M} and {van der Helm-van Mil}, {A H M}",

year = "2016",

doi = "10.1136/annrheumdis-2015-208579",

language = "English",

journal = "Annals of the Rheumatic Diseases",

issn = "1468-2060",

publisher = "BMJ Publishing Group",

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Ajeganova, S, Humphreys, JH, Verheul, MK, van Steenbergen, HW, van Nies, JAB, Hafström, I, Svensson, B, Huizinga, TWJ, Trouw, LA, Verstappen, SMM & van der Helm-van Mil, AHM 2016, 'Anticitrullinated protein antibodies and rheumatoid factor are associated with increased mortality but with different causes of death in patients with rheumatoid arthritis: a longitudinal study in three European cohorts.', Annals of the Rheumatic Diseases. https://doi.org/10.1136/annrheumdis-2015-208579

Anticitrullinated protein antibodies and rheumatoid factor are associated with increased mortality but with different causes of death in patients with rheumatoid arthritis: a longitudinal study in three European cohorts. / Ajeganova, S; Humphreys, J H; Verheul, M K et al.
In: Annals of the Rheumatic Diseases, 2016.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Anticitrullinated protein antibodies and rheumatoid factor are associated with increased mortality but with different causes of death in patients with rheumatoid arthritis: a longitudinal study in three European cohorts.

AU - Ajeganova, S

AU - Humphreys, J H

AU - Verheul, M K

AU - van Steenbergen, H W

AU - van Nies, J A B

AU - Hafström, I

AU - Svensson, Björn

AU - Huizinga, T W J

AU - Trouw, L A

AU - Verstappen, S M M

AU - van der Helm-van Mil, A H M

PY - 2016

Y1 - 2016

N2 - Patients with rheumatoid arthritis (RA)-related autoantibodies have an increased mortality rate. Different autoantibodies are frequently co-occurring and it is unclear which autoantibodies associate with increased mortality. In addition, association with different causes of death is thus far unexplored. Both questions were addressed in three early RA populations.

AB - Patients with rheumatoid arthritis (RA)-related autoantibodies have an increased mortality rate. Different autoantibodies are frequently co-occurring and it is unclear which autoantibodies associate with increased mortality. In addition, association with different causes of death is thus far unexplored. Both questions were addressed in three early RA populations.

U2 - 10.1136/annrheumdis-2015-208579

DO - 10.1136/annrheumdis-2015-208579

M3 - Article

C2 - 26757747

SN - 1468-2060

JO - Annals of the Rheumatic Diseases

JF - Annals of the Rheumatic Diseases

ER -

Ajeganova S, Humphreys JH, Verheul MK, van Steenbergen HW, van Nies JAB, Hafström I et al. Anticitrullinated protein antibodies and rheumatoid factor are associated with increased mortality but with different causes of death in patients with rheumatoid arthritis: a longitudinal study in three European cohorts. Annals of the Rheumatic Diseases. 2016. Epub 2016 Jan 12. doi: 10.1136/annrheumdis-2015-208579