Antiproliferative effects of peracetylated naphthoxylosides.

Ulrika Aili, Mårten Jacobsson, Richard Johnsson, Katrin Mani, Ulf Ellervik

Research output: Contribution to journalArticlepeer-review

6 Citations (SciVal)

Abstract

The antiproliferative activity, and the capability of priming of glycosaminoglycan chains, of two series of peracetylated mono- and bis-xylosylated dihydroxynaphthalenes have been investigated for normal HFL-1 cells, as well as transformed T24 cells, and compared to the unprotected analogs. Our data show increased antiproliferative activity upon peracetylation, but a loss of selectivity towards T24 cells.
Original languageEnglish
Pages (from-to)1763-1766
JournalBioorganic & Medicinal Chemistry Letters
Volume19
DOIs
Publication statusPublished - 2009

Subject classification (UKÄ)

  • Medicinal Chemistry

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