Research output per year
Research output per year
Soumia Taimour, Moncef Zarrouk, Jan Holst, Anders H. Rosengren, Leif Groop, Peter M. Nilsson, Anders Gottsäter
Research output: Contribution to journal › Article › peer-review
Objectives. Type 2 diabetes mellitus has been linked to a decreased risk for abdominal aortic aneurysm (aortic diameter ≥30 mm, AAA) development in men. The aim of this study was to evaluate if such an effect is detectable already around the time of diabetes diagnosis. Design. We cross-sectionally compared aortic diameter at ultrasound screening for AAA in 691 men aged 65 years with incipient or newly diagnosed type 2 diabetes (group A) with 18,262 65-year old control men without diabetes (group B). Results. Aortic diameter did not differ between groups (18.8[17.4–20.8] vs. 19.0[17.5–28.7] mm; p = 0.43). AAA prevalence was 2.5% in group A and 1.5% in group B (p = .010). In logistic regression taking group differences in body mass index (BMI), smoking, presence of atherosclerotic disease and hypertension into account, the difference in AAA prevalence was no longer significant (p = .15). Among men in group A, C-peptide (r = .093; p = .034), but not HbA1c (r = .060; p = .24) correlated with aortic diameter. Conclusion. Among 65 year old men aortic diameter and AAA prevalence do not differ between those with newly diagnosed type 2 diabetes and those without diabetes. Putative protective effects of type 2 diabetes mellitus against aortic dilatation and AAA development therefore probably occur later after diagnosis of diabetes.
Original language | English |
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Pages (from-to) | 202-206 |
Number of pages | 5 |
Journal | Scandinavian Cardiovascular Journal |
Volume | 51 |
Issue number | 4 |
Early online date | 2017 Apr 24 |
DOIs | |
Publication status | Published - 2017 |
Research output: Thesis › Doctoral Thesis (compilation)