Abstract
Three different methods of using protein-based capacitive biosensors for the detection of heavy-metal ions are presented. The metal-binding proteins SmtA, S100A12, MerP and four modified MerPs were immobilised as the bio-recognition element on self-assembled monolayer-modified gold electrodes. Capacitance was measured using potential square step or electrical impedance spectroscopy. The protein-metal interaction generated changes in capacitance mainly due to a protein conformational change.
Original language | English |
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Title of host publication | 2006 International Conference on Nanoscience and Nanotechnology (IEEE Cat. No.06EX1411) |
Publisher | IEEE - Institute of Electrical and Electronics Engineers Inc. |
Pages | 304-307 |
Number of pages | 4 |
ISBN (Print) | 1-4244-0452-5 |
DOIs | |
Publication status | Published - 2006 |
Event | 2006 International Conference on Nanoscience and Nanotechnology - Brisbane, Qld., Australia Duration: 2006 Jul 3 → 2006 Jul 7 |
Conference
Conference | 2006 International Conference on Nanoscience and Nanotechnology |
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Country/Territory | Australia |
City | Brisbane, Qld. |
Period | 2006/07/03 → 2006/07/07 |
Bibliographical note
The information about affiliations in this record was updated in December 2015.The record was previously connected to the following departments: Analytical Chemistry (S/LTH) (011001004)
Subject classification (UKÄ)
- Analytical Chemistry
Free keywords
- electrical impedance spectroscopy
- self-assembled monolayer-modified gold electrodes
- bio-recognition element
- metal-binding proteins
- protein-based capacitive biosensors
- heavy-metal ion detection
- electrochemical capacitance
- environmental application
- biomedical application