Artificial receptors

Bengt Danielsson

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

Abstract

Herein I will provide a brief overview of artificial receptors with emphasis on molecularly imprinted polymers (MIPs) and their applications. Alternative techniques to produce artificial receptors such as in silico designed and modelled polymers as well as different receptors designed using libraries of more or less natural composition will also be mentioned. Examples of these include aptamers and bio-nanocomposites. The physical presentation of the receptors is important and may depend on the application. Block polymerization of MIPs and grinding to particles of suitable size used to be the preferred technique, but today beaded materials can be produced in sizes down to nanobeads and also nanofibers can be used to increase available surface area and thereby capacity. For sensor applications it may be attractive to include the artificial receptors in surface coatings or in membrane structures. Different composite designs can be used to provide additional desirable properties. MIPs and other artificial receptors are gaining rapidly increasing attention in very shifting application areas and an attempt to provide a systematic account for current applications has been made with examples from separation, solid-phase extraction, analysis, carbohydrate specific experiments, and MIPs-directed synthesis.
Original languageEnglish
Title of host publicationBiosensing for the 21st Century (Advances in Biochemical Engineering/Biotechnology)
PublisherSpringer
Pages97-122
Volume109
ISBN (Print)978-3-540-75200-4
DOIs
Publication statusPublished - 2008

Publication series

Name
Volume109
ISSN (Print)0724-6145

Subject classification (UKÄ)

  • Biochemistry and Molecular Biology

Free keywords

  • ion channel sensors
  • aptamers
  • combinatorial libraries
  • MIP catalysis
  • MIPs
  • solid-phase extraction
  • molecularly imprinted polymers

Fingerprint

Dive into the research topics of 'Artificial receptors'. Together they form a unique fingerprint.

Cite this