Abstract
PURPOSE: The aim of this study was to assess the atherosclerotic plaques in a large asymptomatic population stratified based on age and sex.
METHODS: [18F]-2-fluoro-2-deoxy-D-glucose (FDG)-PET/CT of 100 men and 100 women, divided in four age groups were examined to assess FDG-accumulating active, calcified inactive and mixed atherosclerotic plaques in eight defined vessel segments.
RESULTS: There was a high correlation between the total number of cardiovascular risk factors and the number of FDG-accumulating active plaques as well as the number of calcified inactive plaques. There was a significant difference in the number of plaques between all age-groups except for active plaques in age groups 60-70 and 80-90 years.
CONCLUSIONS: There is a correlation between the number of cardiovascular risk factors and the number of FDG-accumulating atherosclerotic lesions in this patient material. Statin-treatment was associated with significantly lower numbers of active plaques.
Original language | English |
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Pages (from-to) | 133-40 |
Number of pages | 8 |
Journal | International Journal of Cardiovascular Imaging |
Volume | 25 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2009 Feb |
Externally published | Yes |
Subject classification (UKÄ)
- Cardiac and Cardiovascular Systems
Free keywords
- Adult
- Age Factors
- Aged
- Aged, 80 and over
- Atherosclerosis
- Cardiovascular Diseases
- Female
- Fluorodeoxyglucose F18
- Humans
- Male
- Middle Aged
- Positron-Emission Tomography
- Radiographic Image Interpretation, Computer-Assisted
- Radiopharmaceuticals
- Risk Factors
- Tomography, X-Ray Computed
- Journal Article
- Research Support, Non-U.S. Gov't