Abstract
Carriers of severe and moderate haemophilia A and B are expected to have approximately 50% of the normal level of factors VIII and IX. However, due to X chromosome inactivation in early embryonic life, factor levels can vary considerably. This can lead to increased bleeding tendency, which may in turn impact on health-related quality of life (HRQOL).
Original language | English |
---|---|
Pages (from-to) | 742-746 |
Journal | Haemophilia |
Volume | 21 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2015 |
Subject classification (UKÄ)
- Hematology