Association between bleeding tendency and health-related quality of life in carriers of moderate and severe haemophilia.

A Olsson; M Hellgren; Erik Berntorp; F Baghaei

doi:10.1111/hae.12796

Association between bleeding tendency and health-related quality of life in carriers of moderate and severe haemophilia.

A Olsson, M Hellgren, Erik Berntorp, F Baghaei

Clinical Coagulation, Malmö

Research output: Contribution to journal › Article › peer-review

Abstract

Carriers of severe and moderate haemophilia A and B are expected to have approximately 50% of the normal level of factors VIII and IX. However, due to X chromosome inactivation in early embryonic life, factor levels can vary considerably. This can lead to increased bleeding tendency, which may in turn impact on health-related quality of life (HRQOL).

Original language	English
Pages (from-to)	742-746
Journal	Haemophilia
Volume	21
Issue number	6
DOIs	https://doi.org/10.1111/hae.12796
Publication status	Published - 2015

Subject classification (UKÄ)

Hematology

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10.1111/hae.12796

http://www.ncbi.nlm.nih.gov/pubmed/26346645?dopt=Abstract

Cite this

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title = "Association between bleeding tendency and health-related quality of life in carriers of moderate and severe haemophilia.",

abstract = "Carriers of severe and moderate haemophilia A and B are expected to have approximately 50\% of the normal level of factors VIII and IX. However, due to X chromosome inactivation in early embryonic life, factor levels can vary considerably. This can lead to increased bleeding tendency, which may in turn impact on health-related quality of life (HRQOL).",

author = "A Olsson and M Hellgren and Erik Berntorp and F Baghaei",

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AU - Olsson, A

AU - Hellgren, M

AU - Berntorp, Erik

AU - Baghaei, F

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N2 - Carriers of severe and moderate haemophilia A and B are expected to have approximately 50% of the normal level of factors VIII and IX. However, due to X chromosome inactivation in early embryonic life, factor levels can vary considerably. This can lead to increased bleeding tendency, which may in turn impact on health-related quality of life (HRQOL).

AB - Carriers of severe and moderate haemophilia A and B are expected to have approximately 50% of the normal level of factors VIII and IX. However, due to X chromosome inactivation in early embryonic life, factor levels can vary considerably. This can lead to increased bleeding tendency, which may in turn impact on health-related quality of life (HRQOL).

UR - https://www.scopus.com/pages/publications/84946495640

U2 - 10.1111/hae.12796

DO - 10.1111/hae.12796

M3 - Article

C2 - 26346645

SN - 1351-8216

VL - 21

SP - 742

EP - 746

JO - Haemophilia

JF - Haemophilia

IS - 6

ER -

Association between bleeding tendency and health-related quality of life in carriers of moderate and severe haemophilia.

Abstract

Subject classification (UKÄ)

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