Association of TCF7L2 variation with single islet autoantibody expression in children with type 1 diabetes.

Maria J Redondo; Jesse Muniz; Luisa M Rodriguez; Dinakar Iyer; Fariba Vaziri Sani; Morey W Haymond; Christiane S Hampe; Michael L Metzker; Struan F A Grant; Ashok Balasubramanyam

doi:10.1136/bmjdrc-2013-000008

Association of TCF7L2 variation with single islet autoantibody expression in children with type 1 diabetes.

Maria J Redondo, Jesse Muniz, Luisa M Rodriguez, Dinakar Iyer, Fariba Vaziri Sani, Morey W Haymond, Christiane S Hampe, Michael L Metzker, Struan F A Grant, Ashok Balasubramanyam

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Abstract

The transcription factor 7-like 2 (TCF7L2) gene has the strongest genetic association with type 2 diabetes. TCF7L2 also associates with latent autoimmune diabetes in adults, which often presents with a single islet autoantibody, but not with classical type 1 diabetes.

Original language	English
Pages (from-to)	e000008
Journal	BMJ open diabetes research & care
Volume	2
Issue number	1
DOIs	https://doi.org/10.1136/bmjdrc-2013-000008
Publication status	Published - 2014

Subject classification (UKÄ)

Endocrinology and Diabetes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1136/bmjdrc-2013-000008

1-s2.0-0009898194900558-main

http://www.ncbi.nlm.nih.gov/pubmed/25452857?dopt=Abstract

Cite this

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title = "Association of TCF7L2 variation with single islet autoantibody expression in children with type 1 diabetes.",

abstract = "The transcription factor 7-like 2 (TCF7L2) gene has the strongest genetic association with type 2 diabetes. TCF7L2 also associates with latent autoimmune diabetes in adults, which often presents with a single islet autoantibody, but not with classical type 1 diabetes.",

author = "Redondo, {Maria J} and Jesse Muniz and Rodriguez, {Luisa M} and Dinakar Iyer and {Vaziri Sani}, Fariba and Haymond, {Morey W} and Hampe, {Christiane S} and Metzker, {Michael L} and Grant, {Struan F A} and Ashok Balasubramanyam",

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AU - Redondo, Maria J

AU - Muniz, Jesse

AU - Rodriguez, Luisa M

AU - Iyer, Dinakar

AU - Vaziri Sani, Fariba

AU - Haymond, Morey W

AU - Hampe, Christiane S

AU - Metzker, Michael L

AU - Grant, Struan F A

AU - Balasubramanyam, Ashok

PY - 2014

Y1 - 2014

N2 - The transcription factor 7-like 2 (TCF7L2) gene has the strongest genetic association with type 2 diabetes. TCF7L2 also associates with latent autoimmune diabetes in adults, which often presents with a single islet autoantibody, but not with classical type 1 diabetes.

AB - The transcription factor 7-like 2 (TCF7L2) gene has the strongest genetic association with type 2 diabetes. TCF7L2 also associates with latent autoimmune diabetes in adults, which often presents with a single islet autoantibody, but not with classical type 1 diabetes.

U2 - 10.1136/bmjdrc-2013-000008

DO - 10.1136/bmjdrc-2013-000008

M3 - Article

C2 - 25452857

SN - 2052-4897

VL - 2

SP - e000008

JO - BMJ open diabetes research & care

JF - BMJ open diabetes research & care

IS - 1

ER -

Association of TCF7L2 variation with single islet autoantibody expression in children with type 1 diabetes.

Abstract

Subject classification (UKÄ)

UN SDGs

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