Atrial Conduction and P-wave Characteristics: From histology to electrophysiology

Yan Huo

Research output: ThesisDoctoral Thesis (compilation)

648 Downloads (Pure)

Abstract

P-wave morphology reflects the projection of the depolarization vector on the electrocardiogram (ECG)lead axes in three-dimentional space and reflects both right and left atrial activation. The main purpose of current thesis was to explore the internal logic between the atrial conduction properties, including intra- and inter- atrial conduction, and P-wave characteristics from the level of histology to electrophysiology.
The current thesis consists of four substudies entitled as: (1) P-wave characteristics and histological atrial abnormalities; (2) Effects of baseline P-wave duration and choice of atrial septal pacing site on shortening atrial activation time during pacing; (3) Diagnosis of atrial tachycardia originating from the lower right atrium: importance of P-wave morphology in the precordial leads V3-V6; and (4) Variability of P-wave morphology predicts the outcome of circumferential pulmonary vein isolation in patients with recurrent atrial fibrillation, respectively.
Original languageEnglish
QualificationDoctor
Awarding Institution
  • Cardiology
Supervisors/Advisors
  • Platonov, Pyotr, Supervisor
  • Holmqvist, Fredrik, Supervisor
  • Bollmann, Andreas, Supervisor
Award date2015 Oct 16
Publisher
ISBN (Print)978-91-7619-183-5
Publication statusPublished - 2015

Bibliographical note

Defence details

Date: 2015-10-16
Time: 09:00
Place: Segerfalksalen, BMC A10, Sölvegatan 17, Lund

External reviewer(s)

Name: Edvardsson, Nils
Title: [unknown]
Affiliation: Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden

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Subject classification (UKÄ)

  • Cardiac and Cardiovascular Systems

Keywords

  • Atrial fibrillation
  • Sinus rhythm
  • Histology
  • Electrophysiology
  • Human
  • P-wave Morphology
  • Variability of P-wave morphology
  • P-wave duration

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