Automated determination of Vinclozolin at the ppb level in aqueous samples by a combination of microporous membrane liquid-liquid extraction and adsorption chromatography

Margareta Sandahl; Erik Úlfsson; Lennart Mathiasson

doi:10.1016/S0003-2670(00)01138-7

Automated determination of Vinclozolin at the ppb level in aqueous samples by a combination of microporous membrane liquid-liquid extraction and adsorption chromatography

Margareta Sandahl, Erik Úlfsson, Lennart Mathiasson

Centre for Analysis and Synthesis

Lund University

Research output: Contribution to journal › Article › peer-review

Abstract

An automated system with microporous membrane liquid-liquid extraction (MMLLE) combined with HPLC has been designed for the determination of Vinclozolin in aqueous matrices. In MMLLE a porous hydrophobic membrane separates an aqueous phase from an organic phase. The pores are filled with the organic solvent. In this work, MMLLE was performed in a flow system and coupled on-line to normal phase HPLC. The performance of the system was evaluated with respect to enrichment when processing large sample volumes. Enrichment factors of 118 times were obtained and the limit of detection was around 1 ng/ml. This technique is an alternative to classical LLE and offers advantages such as reduced solvent consumption, possibility of automation and avoidance of emulsion formations. (C) 2000 Elsevier Science B.V.

Original language	English
Pages (from-to)	1-5
Number of pages	5
Journal	Analytica Chimica Acta
Volume	424
Issue number	1
DOIs	https://doi.org/10.1016/S0003-2670(00)01138-7
Publication status	Published - 2000 Nov 8

Subject classification (UKÄ)

Analytical Chemistry

Free keywords

fungicide
vinclozolin
adsorption
analytic method
article
calibration
chromatography
computer program
flow rate
liquid liquid extraction
priority journal

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10.1016/S0003-2670(00)01138-7

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title = "Automated determination of Vinclozolin at the ppb level in aqueous samples by a combination of microporous membrane liquid-liquid extraction and adsorption chromatography",

abstract = "An automated system with microporous membrane liquid-liquid extraction (MMLLE) combined with HPLC has been designed for the determination of Vinclozolin in aqueous matrices. In MMLLE a porous hydrophobic membrane separates an aqueous phase from an organic phase. The pores are filled with the organic solvent. In this work, MMLLE was performed in a flow system and coupled on-line to normal phase HPLC. The performance of the system was evaluated with respect to enrichment when processing large sample volumes. Enrichment factors of 118 times were obtained and the limit of detection was around 1 ng/ml. This technique is an alternative to classical LLE and offers advantages such as reduced solvent consumption, possibility of automation and avoidance of emulsion formations. (C) 2000 Elsevier Science B.V.",

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T1 - Automated determination of Vinclozolin at the ppb level in aqueous samples by a combination of microporous membrane liquid-liquid extraction and adsorption chromatography

AU - Sandahl, Margareta

AU - Úlfsson, Erik

AU - Mathiasson, Lennart

PY - 2000/11/8

Y1 - 2000/11/8

N2 - An automated system with microporous membrane liquid-liquid extraction (MMLLE) combined with HPLC has been designed for the determination of Vinclozolin in aqueous matrices. In MMLLE a porous hydrophobic membrane separates an aqueous phase from an organic phase. The pores are filled with the organic solvent. In this work, MMLLE was performed in a flow system and coupled on-line to normal phase HPLC. The performance of the system was evaluated with respect to enrichment when processing large sample volumes. Enrichment factors of 118 times were obtained and the limit of detection was around 1 ng/ml. This technique is an alternative to classical LLE and offers advantages such as reduced solvent consumption, possibility of automation and avoidance of emulsion formations. (C) 2000 Elsevier Science B.V.

AB - An automated system with microporous membrane liquid-liquid extraction (MMLLE) combined with HPLC has been designed for the determination of Vinclozolin in aqueous matrices. In MMLLE a porous hydrophobic membrane separates an aqueous phase from an organic phase. The pores are filled with the organic solvent. In this work, MMLLE was performed in a flow system and coupled on-line to normal phase HPLC. The performance of the system was evaluated with respect to enrichment when processing large sample volumes. Enrichment factors of 118 times were obtained and the limit of detection was around 1 ng/ml. This technique is an alternative to classical LLE and offers advantages such as reduced solvent consumption, possibility of automation and avoidance of emulsion formations. (C) 2000 Elsevier Science B.V.

KW - fungicide

KW - vinclozolin

KW - adsorption

KW - analytic method

KW - article

KW - calibration

KW - chromatography

KW - computer program

KW - flow rate

KW - liquid liquid extraction

KW - priority journal

U2 - 10.1016/S0003-2670(00)01138-7

DO - 10.1016/S0003-2670(00)01138-7

M3 - Article

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EP - 5

JO - Analytica Chimica Acta

JF - Analytica Chimica Acta

IS - 1

ER -

Automated determination of Vinclozolin at the ppb level in aqueous samples by a combination of microporous membrane liquid-liquid extraction and adsorption chromatography

Abstract

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