Automatic Measurements of Diameter, Distension and Intima Media Thickness of the Aorta in Premature Rabbit Pups Using B-Mode Images.

Tobias Erlöv, Simon Segstedt, Patrik Milton, Snjolaug Sveinsdottir, Tomas Jansson, Hans W Persson, David Ley, Magnus Cinthio

Research output: Contribution to journalArticlepeer-review

6 Citations (SciVal)

Abstract

To improve cardiovascular research, there is a growing need for arterial characterization in small animals. We developed a method, ARTIC (arterial characterization) for measuring lumen diameter, distension and intima media thickness (IMT). In this study ARTIC was used to automatically characterize the aorta of premature rabbit pups. Automatic measurements were compared with manual measurements, both performed by three observers. Diameter was 769 ± 140 μm (manual) and 766 ± 142 μm (automatic), distension was 35 ± 15 μm (manual) and 40 ± 12 μm (automatic) and IMT was 84 ± 11 μm (manual) and 88 ± 8 μm (automatic) (mean ± standard deviation). The variation in the measured diameter, distension and IMT ranged from 1.1% to 26.0% (manual) and from 1.0% to 9.0% (automatic). The intra-class correlation coefficient ranged from 33.0% to 99.3% (manual) and from 76.9% to 99.6% (automatic). The evaluation revealed that it is feasible to use ARTIC on B-mode images of arteries with small dimensions, which makes it a useful tool for arterial characterization in small animals.
Original languageEnglish
Pages (from-to)371-377
JournalUltrasound in Medicine and Biology
Volume40
Issue number2
DOIs
Publication statusPublished - 2014

Bibliographical note

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Paediatrics (Lund) (013002000), Department of Electrical Measurements (011022000)

Subject classification (UKÄ)

  • Medical Image Processing

Fingerprint

Dive into the research topics of 'Automatic Measurements of Diameter, Distension and Intima Media Thickness of the Aorta in Premature Rabbit Pups Using B-Mode Images.'. Together they form a unique fingerprint.

Cite this