Axonal guidance on patterned free-standing nanowire surfaces

Christelle Prinz; Waldemar Hällström; Thomas Mårtensson; Lars Samuelson; Lars Montelius; Martin Kanje

doi:10.1088/0957-4484/19/34/345101

Axonal guidance on patterned free-standing nanowire surfaces

Christelle Prinz, Waldemar Hällström, Thomas Mårtensson, Lars Samuelson, Lars Montelius, Martin Kanje

Research output: Contribution to journal › Article › peer-review

Abstract

We demonstrate high-fidelity guidance of axons using rows of nanowires. The axons are prevented from crossing the rows, making it possible to guide and sort a large number of axons as opposed to when chemical patterns are used. Focal adhesion forms at the nanowires establishing a possible site of information transfer between the surface and the cells. Rows of gallium phosphide (GaP) nanowires were epitaxially grown on GaP(111) substrates in patterns defined by electron beam lithography.

Original language	English
Article number	345101
Journal	Nanotechnology
Volume	19
Issue number	34
DOIs	https://doi.org/10.1088/0957-4484/19/34/345101
Publication status	Published - 2008

Subject classification (UKÄ)

Nano Technology

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10.1088/0957-4484/19/34/345101

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title = "Axonal guidance on patterned free-standing nanowire surfaces",

abstract = "We demonstrate high-fidelity guidance of axons using rows of nanowires. The axons are prevented from crossing the rows, making it possible to guide and sort a large number of axons as opposed to when chemical patterns are used. Focal adhesion forms at the nanowires establishing a possible site of information transfer between the surface and the cells. Rows of gallium phosphide (GaP) nanowires were epitaxially grown on GaP(111) substrates in patterns defined by electron beam lithography.",

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AU - Prinz, Christelle

AU - Hällström, Waldemar

AU - Mårtensson, Thomas

AU - Samuelson, Lars

AU - Montelius, Lars

AU - Kanje, Martin

PY - 2008

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AB - We demonstrate high-fidelity guidance of axons using rows of nanowires. The axons are prevented from crossing the rows, making it possible to guide and sort a large number of axons as opposed to when chemical patterns are used. Focal adhesion forms at the nanowires establishing a possible site of information transfer between the surface and the cells. Rows of gallium phosphide (GaP) nanowires were epitaxially grown on GaP(111) substrates in patterns defined by electron beam lithography.

U2 - 10.1088/0957-4484/19/34/345101

DO - 10.1088/0957-4484/19/34/345101

M3 - Article

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VL - 19

JO - Nanotechnology

JF - Nanotechnology

IS - 34

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Axonal guidance on patterned free-standing nanowire surfaces

Abstract

Subject classification (UKÄ)

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