B-1 Cells Carry the Memory of Neonatal Immune Imprinting

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Abstract

Group A Streptococcus is a common pathogen that elicits a protective humoral response against the cell wall component GlcNAc. In this issue of Immunity, New et al. demonstrate the ability of long-lived B-1 cells to be programmed by microbial colonization and early life immunization to uniquely incorporate GlcNAc reactivity in mice, establishing their critical role in mediating neonatal immune imprinting.

Original languageEnglish
Pages (from-to)11-13
Number of pages3
JournalImmunity
Volume53
Issue number1
DOIs
Publication statusPublished - 2020

Subject classification (UKÄ)

  • Immunology in the medical area
  • Cell and Molecular Biology

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