Balancing Expectations for Success in Stem Cell-Based Clinical Trials for Parkinson's Disease

Olle Lindvall

doi:10.1016/j.stem.2020.09.002

Balancing Expectations for Success in Stem Cell-Based Clinical Trials for Parkinson's Disease

Research output: Contribution to journal › Article › peer-review

Abstract

Upcoming clinical trials assessing transplantation of stem cell-derived dopaminergic neurons into the striatum in patients with Parkinson's disease could generate groundbreaking results on neuronal replacement in the human brain. However, as highlighted here, the road toward a clinically competitive treatment for this multisystem disorder will probably be long and winding.

Original language	English
Pages (from-to)	519-522
Number of pages	4
Journal	Cell Stem Cell
Volume	27
Issue number	4
DOIs	https://doi.org/10.1016/j.stem.2020.09.002
Publication status	Published - 2020

Subject classification (UKÄ)

Neurosciences

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.stem.2020.09.002

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title = "Balancing Expectations for Success in Stem Cell-Based Clinical Trials for Parkinson's Disease",

abstract = "Upcoming clinical trials assessing transplantation of stem cell-derived dopaminergic neurons into the striatum in patients with Parkinson's disease could generate groundbreaking results on neuronal replacement in the human brain. However, as highlighted here, the road toward a clinically competitive treatment for this multisystem disorder will probably be long and winding.",

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AB - Upcoming clinical trials assessing transplantation of stem cell-derived dopaminergic neurons into the striatum in patients with Parkinson's disease could generate groundbreaking results on neuronal replacement in the human brain. However, as highlighted here, the road toward a clinically competitive treatment for this multisystem disorder will probably be long and winding.

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DO - 10.1016/j.stem.2020.09.002

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Balancing Expectations for Success in Stem Cell-Based Clinical Trials for Parkinson's Disease

Abstract

Subject classification (UKÄ)

UN SDGs

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