Abstract
All the cells of the individuals with phenotypes "p" y "Pk" lack the glucidic antigens of "public" blood groups. These subjects form natural and regular antibodies against the missing structures (anti-P, anti-PP1 y anti-PP1Pk) that agglutínate or hemolyze the red-blood cells of every individual, excepting those with the same phenotype. Due to the exceptional character of these pictures (a few individuals per million) and their association with severe transfusional hemolytic reactions and repeated miscarriages, these subjects should be identified and characterized.
Translated title of the contribution | Molecular bases and clinical importance of the exceptional phenotypes of blood group P and PK |
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Original language | Spanish |
Journal | Revista Cubana de Hematologia, Inmunologia y Hemoterapia |
Volume | 24 |
Issue number | 3 |
Publication status | Published - 2008 Sept |
Bibliographical note
Copyright:Copyright 2009 Elsevier B.V., All rights reserved.
Subject classification (UKÄ)
- Hematology
- Immunology in the medical area
Free keywords
- Alloimmunization
- Blood group
- Erythrocyte
- Gestation
- Glycosyltransferases
- Transfusion