Bases moleculares e importancia clínica de los excepcionales fenotipos de grupo sanguíneo P y PK

Translated title of the contribution: Molecular bases and clinical importance of the exceptional phenotypes of blood group P and PK

Daniel De La Vega Elena, Asa Hellberg, Mario Pivetta, Miguel Ángel Raillon, Sergio Chialina, E. Solis, Martin L Olsson

Research output: Contribution to journalReview articlepeer-review

Abstract

All the cells of the individuals with phenotypes "p" y "Pk" lack the glucidic antigens of "public" blood groups. These subjects form natural and regular antibodies against the missing structures (anti-P, anti-PP1 y anti-PP1Pk) that agglutínate or hemolyze the red-blood cells of every individual, excepting those with the same phenotype. Due to the exceptional character of these pictures (a few individuals per million) and their association with severe transfusional hemolytic reactions and repeated miscarriages, these subjects should be identified and characterized.

Translated title of the contributionMolecular bases and clinical importance of the exceptional phenotypes of blood group P and PK
Original languageSpanish
JournalRevista Cubana de Hematologia, Inmunologia y Hemoterapia
Volume24
Issue number3
Publication statusPublished - 2008 Sept

Bibliographical note

Copyright:
Copyright 2009 Elsevier B.V., All rights reserved.

Subject classification (UKÄ)

  • Hematology
  • Immunology in the medical area

Free keywords

  • Alloimmunization
  • Blood group
  • Erythrocyte
  • Gestation
  • Glycosyltransferases
  • Transfusion

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