Beta camera low activity tumor imaging

Kaj Ljunggren, Sven-Erik Strand, Crister Ceberg, Hans Sjöholm, Dan Elmqvist, Arne Brun, Leif Salford

Research output: Contribution to journalArticlepeer-review


A new technique, the beta camera, to complement film autoradiography, with fast quantitative imaging of beta particle-emitting radionuclides has been developed. It consists of a thin plastic scintillator and a light-sensitive microchannel plate detector. The thin tissue sample is mounted on the scintillator. Our first system had a high background and a moderate spatial resolution of 900 microns. We now report an improved system with a photomultiplier tube mounted on the scintillator of the microchannel plate detector. Only events registered by both detectors are accepted. A fast coincidence unit processes the signals, and if a time overlap exists, an event is generated in the beta camera. In the coincidence mode, images with low activity distribution of 201Tl (count rate 1 s-1) in 50 microns-thick slices of a human glioma tumor could be recorded with a spatial resolution of 500 microns.
Original languageEnglish
Pages (from-to)869-872
JournalActa Oncologica
Issue number7-8
Publication statusPublished - 1993

Bibliographical note

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Radiation Physics, Lund (013034000), Neurosurgery (013026000), Pathology, (Lund) (013030000)

Subject classification (UKÄ)

  • Cancer and Oncology


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