Biological Structures

Zoe Fisher, Andrew Jackson, Andrey Kovalevsky, Esko Oksanen, Hanna Wacklin

Research output: Chapter in Book/Report/Conference proceedingBook chapterpeer-review

7 Citations (SciVal)

Abstract

Neutron scattering methods are excellent for probing the detailed structure of biological systems, which rely on the intricate interplay of a large number of molecules from proteins and nucleic acids to lipids, hormones, and metabolites. With recent instrument developments and emergence of both new neutron sources and techniques, many biological systems that are not yet amenable to characterization by neutron scattering will become accessible in the near future, which will allow new experiments to be developed with a range of biologically relevant samples, offering new insights in life science. In this chapter, we will describe neutron methods for biological structure characterization on different length scales from atomic resolution to macromolecular length scales-up to micrometers. The dynamics of biological molecules are described by Seydel in Chapter 2 of this thematic volume.

Original languageEnglish
Title of host publicationExperimental Methods in the Physical Sciences
PublisherAcademic Press
Pages1-75
Number of pages75
Volume49
DOIs
Publication statusPublished - 2017

Publication series

NameExperimental Methods in the Physical Sciences
Volume49
ISSN (Print)10794042

Subject classification (UKÄ)

  • Structural Biology

Keywords

  • Crystallization
  • Deuteration
  • Macromolecular diffraction
  • Reflectometry
  • Small-angle neutron scattering

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