Biomarkers of early chronic obstructive pulmonary disease (COPD) in smokers and former smokers. Protocol of a longitudinal study.

Mikael Truedsson; Johan Malm; Barbara Sahlin; May Bugge; Elisabet Wieslander; Magnus Dahlbäck; Roger Appelqvist; Thomas Fehniger; György Marko-Varga

doi:10.1186/s40169-016-0086-5

Biomarkers of early chronic obstructive pulmonary disease (COPD) in smokers and former smokers. Protocol of a longitudinal study.

Mikael Truedsson, Johan Malm, Barbara Sahlin, May Bugge, Elisabet Wieslander, Magnus Dahlbäck, Roger Appelqvist, Thomas Fehniger, György Marko-Varga

Research output: Contribution to journal › Article › peer-review

Abstract

Chronic obstructive pulmonary disease (COPD) is an irreversible disease, diagnosed predominantly in smokers. COPD is currently the third leading cause of death worldwide. Far more than 15 % of smokers get COPD: in fact, most develop some amount of pulmonary impairment. Smoking-related COPD is associated with both acute exacerbations and is closely correlated to comorbidities, such as cardiovascular disease and lung cancer. The objective of our study (KOL-Örestad) is to identify biomarkers in smokers and ex-smokers, with early signs of COPD, and compare these biomarkers with those of non-smokers and healthy smokers/ex-smokers. The participants in the study are recruited from Örestadskliniken, a primary health care clinic in Malmö, Sweden.

Original language	English
Article number	9
Journal	Clinical and Translational Medicine
Volume	5
Issue number	1
DOIs	https://doi.org/10.1186/s40169-016-0086-5
Publication status	Published - 2016

Subject classification (UKÄ)

Respiratory Medicine and Allergy
Biomaterials Science

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1186/s40169-016-0086-5

http://www.ncbi.nlm.nih.gov/pubmed/26951192?dopt=Abstract

Cite this

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abstract = "Chronic obstructive pulmonary disease (COPD) is an irreversible disease, diagnosed predominantly in smokers. COPD is currently the third leading cause of death worldwide. Far more than 15 % of smokers get COPD: in fact, most develop some amount of pulmonary impairment. Smoking-related COPD is associated with both acute exacerbations and is closely correlated to comorbidities, such as cardiovascular disease and lung cancer. The objective of our study (KOL-{\"O}restad) is to identify biomarkers in smokers and ex-smokers, with early signs of COPD, and compare these biomarkers with those of non-smokers and healthy smokers/ex-smokers. The participants in the study are recruited from {\"O}restadskliniken, a primary health care clinic in Malm{\"o}, Sweden.",

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AU - Truedsson, Mikael

AU - Malm, Johan

AU - Sahlin, Barbara

AU - Bugge, May

AU - Wieslander, Elisabet

AU - Dahlbäck, Magnus

AU - Appelqvist, Roger

AU - Fehniger, Thomas

AU - Marko-Varga, György

PY - 2016

Y1 - 2016

N2 - Chronic obstructive pulmonary disease (COPD) is an irreversible disease, diagnosed predominantly in smokers. COPD is currently the third leading cause of death worldwide. Far more than 15 % of smokers get COPD: in fact, most develop some amount of pulmonary impairment. Smoking-related COPD is associated with both acute exacerbations and is closely correlated to comorbidities, such as cardiovascular disease and lung cancer. The objective of our study (KOL-Örestad) is to identify biomarkers in smokers and ex-smokers, with early signs of COPD, and compare these biomarkers with those of non-smokers and healthy smokers/ex-smokers. The participants in the study are recruited from Örestadskliniken, a primary health care clinic in Malmö, Sweden.

AB - Chronic obstructive pulmonary disease (COPD) is an irreversible disease, diagnosed predominantly in smokers. COPD is currently the third leading cause of death worldwide. Far more than 15 % of smokers get COPD: in fact, most develop some amount of pulmonary impairment. Smoking-related COPD is associated with both acute exacerbations and is closely correlated to comorbidities, such as cardiovascular disease and lung cancer. The objective of our study (KOL-Örestad) is to identify biomarkers in smokers and ex-smokers, with early signs of COPD, and compare these biomarkers with those of non-smokers and healthy smokers/ex-smokers. The participants in the study are recruited from Örestadskliniken, a primary health care clinic in Malmö, Sweden.

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DO - 10.1186/s40169-016-0086-5

M3 - Article

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SN - 2001-1326

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JO - Clinical and Translational Medicine

JF - Clinical and Translational Medicine

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ER -

Biomarkers of early chronic obstructive pulmonary disease (COPD) in smokers and former smokers. Protocol of a longitudinal study.

Abstract

Subject classification (UKÄ)

UN SDGs

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