Bone density 11 years after anorexia nervosa onset in a controlled study of 39 cases

Elisabet Wentz, Dan Mellström, Christopher Gillberg, Valter Sundh, Carina Gillberg, Maria Råstam

Research output: Contribution to journalArticlepeer-review

Abstract

Objective
To evaluate bone mineral density (BMD) and body composition 11 years after the onset of anorexia nervosa (AN).

Method
Thirty-nine AN subjects (36 females, 3 males), selected from a population-based sample, and 46 matched controls (COMP; 43 females, 3 males) were examined by using double-energy X-ray absorptiometry (DXA). Only 2 women still had AN. None of the men had AN.

Results
The females in the AN and COMP groups did not differ regarding BMD, nor was there a difference across female groups concerning body mass index (BMI). The female AN group had a significantly lower percentage of body fat. BMD among females in the AN group was related to lowest BMI ever. There was an inverse relationship between lumbar BMD and AN duration.

Discussion
Low BMD is not overrepresented among weight-restored AN patients at long-term follow-up compared with healthy women. However, the inverse relationship between BMD and AN duration may be indicative of a risk for osteopenia in patients with subchronic and chronic AN.
Original languageEnglish
Pages (from-to)314-8
JournalInternational Journal of Eating Disorders
Volume34
Issue number3
DOIs
Publication statusPublished - 2003
Externally publishedYes

Subject classification (UKÄ)

  • Psychiatry

Free keywords

  • AdolescentAdultAnorexia Nervosa/complications*Body Composition*Body WeightBone Density*Bone Diseases
  • Metabolic/etiologyCase-Control StudiesFemaleFollow-Up StudiesHumansMaleRisk Factors

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