Breast cancer risk in relation to abortion: Results from the EPIC study

Gillian K. Reeves; Sau-Wan Kan; Tim Key; Anne Tjonneland; Anja Olsen; Kim Overvad; Petra H. Peeters; Francoise Clavel-Chapelon; Xavier Paoletti; Franco Berrino; Vittorio Krogh; Domenico Palli; Rosario Tumino; Salvatore Panico; Paulo Vineis; Carlos A. Gonzalez; Eva Ardanaz; Carmen Martinez; Pilar Amiano; Jose R. Quiros; Maria R. Tormo; Kay-Tee Khaw; Antonia Trichopoulou; Theodora Psaltopoulou; Victoria Kalaothaki; Gabriele Nagel; Jenny Chang-Claude; Heiner Boeing; Petra H. Lahmann; Elisabet Wirfält; Rudolf Kaaks; Elio Riboli

doi:10.1002/ijc.22001

Breast cancer risk in relation to abortion: Results from the EPIC study

Gillian K. Reeves, Sau-Wan Kan, Tim Key, Anne Tjonneland, Anja Olsen, Kim Overvad, Petra H. Peeters, Francoise Clavel-Chapelon, Xavier Paoletti, Franco Berrino, Vittorio Krogh, Domenico Palli, Rosario Tumino, Salvatore Panico, Paulo Vineis, Carlos A. Gonzalez, Eva Ardanaz, Carmen Martinez, Pilar Amiano, Jose R. QuirosMaria R. Tormo, Kay-Tee Khaw, Antonia Trichopoulou, Theodora Psaltopoulou, Victoria Kalaothaki, Gabriele Nagel, Jenny Chang-Claude, Heiner Boeing, Petra H. Lahmann, Elisabet Wirfält, Rudolf Kaaks, Elio Riboli

Nutrition Epidemiology

Research output: Contribution to journal › Article › peer-review

Abstract

The role of spontaneous and induced abortion on breast cancer risk is examined among 267,361 women recruited into the European Prospective Investigation into Cancer and nutrition between 1992 and 2000. The data were collected from 20 centers, across 9 countries, and included information on a total of 4,805 women with breast cancer, of whom 1,657 reported having ever had any type of abortion. Overall, the relative risk of breast cancer in women who reported ever having had a spontaneous abortion was not significantly elevated when compared with women who reported never having had such an abortion (RR = 1.07, 95 % CI = 0.99-1.14). However, there was some evidence of a slight increase in the risk of breast cancer among women who reported having had 2 or more spontaneous abortions (1.20,1.07-1.35). The relative risk of breast cancer among women who reported ever having had an induced abortion when compared to women who reported never having had an induced abortion was 0.95 (0.87-1.03). Overall, the findings provide further unbiased evidence of the lack of an adverse effect of induced abortion on breast cancer risk. (c) 2006 Wiley-Liss, Inc.

Original language	English
Pages (from-to)	1741-1745
Journal	International Journal of Cancer
Volume	119
Issue number	7
DOIs	https://doi.org/10.1002/ijc.22001
Publication status	Published - 2006

Subject classification (UKÄ)

Cancer and Oncology

Free keywords

recall bias
induced abortion
breast cancer
spontaneous abortion
prospective data

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/ijc.22001

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Reeves, G. K., Kan, S.-W., Key, T., Tjonneland, A., Olsen, A., Overvad, K., Peeters, P. H., Clavel-Chapelon, F., Paoletti, X., Berrino, F., Krogh, V., Palli, D., Tumino, R., Panico, S., Vineis, P., Gonzalez, C. A., Ardanaz, E., Martinez, C., Amiano, P., ... Riboli, E. (2006). Breast cancer risk in relation to abortion: Results from the EPIC study. International Journal of Cancer, 119(7), 1741-1745. https://doi.org/10.1002/ijc.22001

@article{7c47052b2d7f4bada6a6b475c6b2b4e3,

title = "Breast cancer risk in relation to abortion: Results from the EPIC study",

abstract = "The role of spontaneous and induced abortion on breast cancer risk is examined among 267,361 women recruited into the European Prospective Investigation into Cancer and nutrition between 1992 and 2000. The data were collected from 20 centers, across 9 countries, and included information on a total of 4,805 women with breast cancer, of whom 1,657 reported having ever had any type of abortion. Overall, the relative risk of breast cancer in women who reported ever having had a spontaneous abortion was not significantly elevated when compared with women who reported never having had such an abortion (RR = 1.07, 95 % CI = 0.99-1.14). However, there was some evidence of a slight increase in the risk of breast cancer among women who reported having had 2 or more spontaneous abortions (1.20,1.07-1.35). The relative risk of breast cancer among women who reported ever having had an induced abortion when compared to women who reported never having had an induced abortion was 0.95 (0.87-1.03). Overall, the findings provide further unbiased evidence of the lack of an adverse effect of induced abortion on breast cancer risk. (c) 2006 Wiley-Liss, Inc.",

keywords = "recall bias, induced abortion, breast cancer, spontaneous abortion, prospective data",

author = "Reeves, {Gillian K.} and Sau-Wan Kan and Tim Key and Anne Tjonneland and Anja Olsen and Kim Overvad and Peeters, {Petra H.} and Francoise Clavel-Chapelon and Xavier Paoletti and Franco Berrino and Vittorio Krogh and Domenico Palli and Rosario Tumino and Salvatore Panico and Paulo Vineis and Gonzalez, {Carlos A.} and Eva Ardanaz and Carmen Martinez and Pilar Amiano and Quiros, {Jose R.} and Tormo, {Maria R.} and Kay-Tee Khaw and Antonia Trichopoulou and Theodora Psaltopoulou and Victoria Kalaothaki and Gabriele Nagel and Jenny Chang-Claude and Heiner Boeing and Lahmann, {Petra H.} and Elisabet Wirf{\"a}lt and Rudolf Kaaks and Elio Riboli",

year = "2006",

doi = "10.1002/ijc.22001",

language = "English",

volume = "119",

pages = "1741--1745",

journal = "International Journal of Cancer",

issn = "0020-7136",

publisher = "John Wiley & Sons Inc.",

number = "7",

}

Reeves, GK, Kan, S-W, Key, T, Tjonneland, A, Olsen, A, Overvad, K, Peeters, PH, Clavel-Chapelon, F, Paoletti, X, Berrino, F, Krogh, V, Palli, D, Tumino, R, Panico, S, Vineis, P, Gonzalez, CA, Ardanaz, E, Martinez, C, Amiano, P, Quiros, JR, Tormo, MR, Khaw, K-T, Trichopoulou, A, Psaltopoulou, T, Kalaothaki, V, Nagel, G, Chang-Claude, J, Boeing, H, Lahmann, PH, Wirfält, E, Kaaks, R & Riboli, E 2006, 'Breast cancer risk in relation to abortion: Results from the EPIC study', International Journal of Cancer, vol. 119, no. 7, pp. 1741-1745. https://doi.org/10.1002/ijc.22001

TY - JOUR

T1 - Breast cancer risk in relation to abortion: Results from the EPIC study

AU - Reeves, Gillian K.

AU - Kan, Sau-Wan

AU - Key, Tim

AU - Tjonneland, Anne

AU - Olsen, Anja

AU - Overvad, Kim

AU - Peeters, Petra H.

AU - Clavel-Chapelon, Francoise

AU - Paoletti, Xavier

AU - Berrino, Franco

AU - Krogh, Vittorio

AU - Palli, Domenico

AU - Tumino, Rosario

AU - Panico, Salvatore

AU - Vineis, Paulo

AU - Gonzalez, Carlos A.

AU - Ardanaz, Eva

AU - Martinez, Carmen

AU - Amiano, Pilar

AU - Quiros, Jose R.

AU - Tormo, Maria R.

AU - Khaw, Kay-Tee

AU - Trichopoulou, Antonia

AU - Psaltopoulou, Theodora

AU - Kalaothaki, Victoria

AU - Nagel, Gabriele

AU - Chang-Claude, Jenny

AU - Boeing, Heiner

AU - Lahmann, Petra H.

AU - Wirfält, Elisabet

AU - Kaaks, Rudolf

AU - Riboli, Elio

PY - 2006

Y1 - 2006

N2 - The role of spontaneous and induced abortion on breast cancer risk is examined among 267,361 women recruited into the European Prospective Investigation into Cancer and nutrition between 1992 and 2000. The data were collected from 20 centers, across 9 countries, and included information on a total of 4,805 women with breast cancer, of whom 1,657 reported having ever had any type of abortion. Overall, the relative risk of breast cancer in women who reported ever having had a spontaneous abortion was not significantly elevated when compared with women who reported never having had such an abortion (RR = 1.07, 95 % CI = 0.99-1.14). However, there was some evidence of a slight increase in the risk of breast cancer among women who reported having had 2 or more spontaneous abortions (1.20,1.07-1.35). The relative risk of breast cancer among women who reported ever having had an induced abortion when compared to women who reported never having had an induced abortion was 0.95 (0.87-1.03). Overall, the findings provide further unbiased evidence of the lack of an adverse effect of induced abortion on breast cancer risk. (c) 2006 Wiley-Liss, Inc.

AB - The role of spontaneous and induced abortion on breast cancer risk is examined among 267,361 women recruited into the European Prospective Investigation into Cancer and nutrition between 1992 and 2000. The data were collected from 20 centers, across 9 countries, and included information on a total of 4,805 women with breast cancer, of whom 1,657 reported having ever had any type of abortion. Overall, the relative risk of breast cancer in women who reported ever having had a spontaneous abortion was not significantly elevated when compared with women who reported never having had such an abortion (RR = 1.07, 95 % CI = 0.99-1.14). However, there was some evidence of a slight increase in the risk of breast cancer among women who reported having had 2 or more spontaneous abortions (1.20,1.07-1.35). The relative risk of breast cancer among women who reported ever having had an induced abortion when compared to women who reported never having had an induced abortion was 0.95 (0.87-1.03). Overall, the findings provide further unbiased evidence of the lack of an adverse effect of induced abortion on breast cancer risk. (c) 2006 Wiley-Liss, Inc.

KW - recall bias

KW - induced abortion

KW - breast cancer

KW - spontaneous abortion

KW - prospective data

U2 - 10.1002/ijc.22001

DO - 10.1002/ijc.22001

M3 - Article

SN - 0020-7136

VL - 119

SP - 1741

EP - 1745

JO - International Journal of Cancer

JF - International Journal of Cancer

IS - 7

ER -

Breast cancer risk in relation to abortion: Results from the EPIC study

Abstract

Subject classification (UKÄ)

Free keywords

UN SDGs

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