Cancer - An Insurgency of Clones

David Gisselsson; Robert Egnell

doi:10.1016/j.trecan.2016.11.010

Cancer - An Insurgency of Clones

Research output: Contribution to journal › Article › peer-review

Abstract

Oncological therapy resembles a military force that eliminates the central power of a country (dominant clone of a cancer) to create a vacuum where insurgents (subclones) thrive and instigate rebellion (relapse). We suggest that military counterinsurgency doctrine can inspire a discussion of cancer that uniquely embraces both cancer cell evolution and tumour microenvironment.

Original language	English
Pages (from-to)	73-75
Journal	Trends in Cancer
Volume	3
Issue number	2
DOIs	https://doi.org/10.1016/j.trecan.2016.11.010
Publication status	Published - 2017

Subject classification (UKÄ)

Cancer and Oncology

Free keywords

Cancer
Counterinsurgency
Evolution
Microenvironment

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.trecan.2016.11.010

Cite this

@article{ae02238f5d4b415395adb84694c4dce0,

title = "Cancer - An Insurgency of Clones",

abstract = "Oncological therapy resembles a military force that eliminates the central power of a country (dominant clone of a cancer) to create a vacuum where insurgents (subclones) thrive and instigate rebellion (relapse). We suggest that military counterinsurgency doctrine can inspire a discussion of cancer that uniquely embraces both cancer cell evolution and tumour microenvironment.",

keywords = "Cancer, Counterinsurgency, Evolution, Microenvironment",

author = "David Gisselsson and Robert Egnell",

year = "2017",

doi = "10.1016/j.trecan.2016.11.010",

language = "English",

volume = "3",

pages = "73--75",

journal = "Trends in Cancer",

issn = "2405-8033",

publisher = "Cell Press",

number = "2",

}

TY - JOUR

T1 - Cancer - An Insurgency of Clones

AU - Gisselsson, David

AU - Egnell, Robert

PY - 2017

Y1 - 2017

N2 - Oncological therapy resembles a military force that eliminates the central power of a country (dominant clone of a cancer) to create a vacuum where insurgents (subclones) thrive and instigate rebellion (relapse). We suggest that military counterinsurgency doctrine can inspire a discussion of cancer that uniquely embraces both cancer cell evolution and tumour microenvironment.

AB - Oncological therapy resembles a military force that eliminates the central power of a country (dominant clone of a cancer) to create a vacuum where insurgents (subclones) thrive and instigate rebellion (relapse). We suggest that military counterinsurgency doctrine can inspire a discussion of cancer that uniquely embraces both cancer cell evolution and tumour microenvironment.

KW - Cancer

KW - Counterinsurgency

KW - Evolution

KW - Microenvironment

UR - http://www.scopus.com/inward/record.url?scp=85009251532&partnerID=8YFLogxK

U2 - 10.1016/j.trecan.2016.11.010

DO - 10.1016/j.trecan.2016.11.010

M3 - Article

C2 - 28718446

AN - SCOPUS:85009251532

SN - 2405-8033

VL - 3

SP - 73

EP - 75

JO - Trends in Cancer

JF - Trends in Cancer

IS - 2

ER -

Cancer - An Insurgency of Clones

Abstract

Subject classification (UKÄ)

Free keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this