Cancer-associated Changes in the Expression of TMPRSS2-ERG, PCA3, and SPINK1 in Histologically Benign Tissue From Cancerous vs Noncancerous Prostatectomy Specimens.

Riina-Minna Väänänen; Hans Lilja; Leni Kauko; Pauliina Helo; Henna Kekki; Angel M Cronin; Andrew J Vickers; Martti Nurmi; Kalle Alanen; Anders Bjartell; Kim Pettersson

doi:10.1016/j.urology.2013.11.005

Cancer-associated Changes in the Expression of TMPRSS2-ERG, PCA3, and SPINK1 in Histologically Benign Tissue From Cancerous vs Noncancerous Prostatectomy Specimens.

Riina-Minna Väänänen, Hans Lilja, Leni Kauko, Pauliina Helo, Henna Kekki, Angel M Cronin, Andrew J Vickers, Martti Nurmi, Kalle Alanen, Anders Bjartell, Kim Pettersson

Research output: Contribution to journal › Article › peer-review

222 Downloads (Pure)

Abstract

To investigate whether messenger ribonucleic acid (mRNA) expression of TMPRSS2-ERG fusion gene, a suggested prostate cancer (PCa) biomarker, was specific to cancerous lesions alone and to study the expression of SPINK1 and PCA3 mRNAs in the same cohort to also explore the proposed mutual exclusivity of TMPRSS2-ERG and SPINK1 expression.

Original language	English
Pages (from-to)	511.e1-511.e7
Journal	Urology
Volume	83
Issue number	2
DOIs	https://doi.org/10.1016/j.urology.2013.11.005
Publication status	Published - 2014

Subject classification (UKÄ)

Urology and Nephrology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.urology.2013.11.005

TMPRSS2-ERG_paper_-_VaIaInaInen_2013_vConf

http://www.ncbi.nlm.nih.gov/pubmed/24468524?dopt=Abstract

Cite this

Väänänen, R.-M., Lilja, H., Kauko, L., Helo, P., Kekki, H., Cronin, A. M., Vickers, A. J., Nurmi, M., Alanen, K., Bjartell, A., & Pettersson, K. (2014). Cancer-associated Changes in the Expression of TMPRSS2-ERG, PCA3, and SPINK1 in Histologically Benign Tissue From Cancerous vs Noncancerous Prostatectomy Specimens. Urology, 83(2), 511.e1-511.e7. https://doi.org/10.1016/j.urology.2013.11.005

@article{140f366d9c7842d7b08f7f43098cac4c,

title = "Cancer-associated Changes in the Expression of TMPRSS2-ERG, PCA3, and SPINK1 in Histologically Benign Tissue From Cancerous vs Noncancerous Prostatectomy Specimens.",

abstract = "To investigate whether messenger ribonucleic acid (mRNA) expression of TMPRSS2-ERG fusion gene, a suggested prostate cancer (PCa) biomarker, was specific to cancerous lesions alone and to study the expression of SPINK1 and PCA3 mRNAs in the same cohort to also explore the proposed mutual exclusivity of TMPRSS2-ERG and SPINK1 expression.",

author = "Riina-Minna V{\"a}{\"a}n{\"a}nen and Hans Lilja and Leni Kauko and Pauliina Helo and Henna Kekki and Cronin, {Angel M} and Vickers, {Andrew J} and Martti Nurmi and Kalle Alanen and Anders Bjartell and Kim Pettersson",

year = "2014",

doi = "10.1016/j.urology.2013.11.005",

language = "English",

volume = "83",

pages = "511.e1--511.e7",

journal = "Urology",

issn = "1527-9995",

publisher = "Elsevier",

number = "2",

}

Väänänen, R-M, Lilja, H, Kauko, L, Helo, P, Kekki, H, Cronin, AM, Vickers, AJ, Nurmi, M, Alanen, K, Bjartell, A & Pettersson, K 2014, 'Cancer-associated Changes in the Expression of TMPRSS2-ERG, PCA3, and SPINK1 in Histologically Benign Tissue From Cancerous vs Noncancerous Prostatectomy Specimens.', Urology, vol. 83, no. 2, pp. 511.e1-511.e7. https://doi.org/10.1016/j.urology.2013.11.005

TY - JOUR

T1 - Cancer-associated Changes in the Expression of TMPRSS2-ERG, PCA3, and SPINK1 in Histologically Benign Tissue From Cancerous vs Noncancerous Prostatectomy Specimens.

AU - Väänänen, Riina-Minna

AU - Lilja, Hans

AU - Kauko, Leni

AU - Helo, Pauliina

AU - Kekki, Henna

AU - Cronin, Angel M

AU - Vickers, Andrew J

AU - Nurmi, Martti

AU - Alanen, Kalle

AU - Bjartell, Anders

AU - Pettersson, Kim

PY - 2014

Y1 - 2014

N2 - To investigate whether messenger ribonucleic acid (mRNA) expression of TMPRSS2-ERG fusion gene, a suggested prostate cancer (PCa) biomarker, was specific to cancerous lesions alone and to study the expression of SPINK1 and PCA3 mRNAs in the same cohort to also explore the proposed mutual exclusivity of TMPRSS2-ERG and SPINK1 expression.

AB - To investigate whether messenger ribonucleic acid (mRNA) expression of TMPRSS2-ERG fusion gene, a suggested prostate cancer (PCa) biomarker, was specific to cancerous lesions alone and to study the expression of SPINK1 and PCA3 mRNAs in the same cohort to also explore the proposed mutual exclusivity of TMPRSS2-ERG and SPINK1 expression.

U2 - 10.1016/j.urology.2013.11.005

DO - 10.1016/j.urology.2013.11.005

M3 - Article

C2 - 24468524

SN - 1527-9995

VL - 83

SP - 511.e1-511.e7

JO - Urology

JF - Urology

IS - 2

ER -

Cancer-associated Changes in the Expression of TMPRSS2-ERG, PCA3, and SPINK1 in Histologically Benign Tissue From Cancerous vs Noncancerous Prostatectomy Specimens.

Abstract

Subject classification (UKÄ)

UN SDGs

Access to Document

Fingerprint

Cite this