Abstract
Capacitive binding assays have long been considered highly sensitive. The underlying method in such assays includes sending short potential pulses and then registering the current. However, with the introduction of current pulses and registration of potential responses, the stability improved significantly, leading to assays of extreme sensitivities. The new assaying technology has been applied in a range of affinity binding assays, from immunoassays via DNA base pairing to the use of molecularly imprinted polymers (MIPs). Overall, very good sensitivities have been recorded, and the MIPs exhibit high stability and reusability.
Original language | English |
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Pages (from-to) | 233-238 |
Number of pages | 6 |
Journal | Trac. Trends in Analytical Chemistry |
Volume | 79 |
DOIs | |
Publication status | Published - 2016 May 1 |
Subject classification (UKÄ)
- Analytical Chemistry
Free keywords
- Affinity biosensor
- Capacitive transduction
- Electropolymerization
- Gold surface
- Microcontact imprinting
- MIP
- Ultra-sensitive