Abstract
Our results demonstrate that (1) CD103 is upregulated on CD8(+) T cells subsequent to their entry into the small intestinal epithelium, and (2) that the chemokine CCL25 enhances CD103-mediated adhesion to E-cadherin. These results suggest a novel role for chemokines in modulating interactions between lymphocytes and epithelial cells at mucosal surfaces.
| Original language | English |
|---|---|
| Pages (from-to) | 334-336 |
| Journal | Annals of the New York Academy of Sciences |
| Volume | 1029 |
| DOIs | |
| Publication status | Published - 2004 |
Subject classification (UKÄ)
- Basic Medicine
Free keywords
- CCL25
- CD103
- CD8+ T cells
- E-cadherin