Cell proliferation, measured as flow cytometric S-phase fraction, is a strong prognostic indicator in FIGO stage I endometrioid endometrial carcinoma: a population-based study.

Rasmus W Green; Sanna Engblom; Bo Baldetorp; Linda Werner Hartman; Anna Måsbäck; Maria Bjurberg

doi:10.1111/aogs.12704

Cell proliferation, measured as flow cytometric S-phase fraction, is a strong prognostic indicator in FIGO stage I endometrioid endometrial carcinoma: a population-based study.

Rasmus W Green, Sanna Engblom, Bo Baldetorp, Linda Werner Hartman, Anna Måsbäck, Maria Bjurberg

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Abstract

In early-stage endometrial carcinoma, there is controversy regarding the prognostic value of the flow cytometric variables DNA ploidy (diploid vs. aneuploid) and S-phase fraction. In Sweden, the former is included in national guidelines despite poor scientific support and the latter is not used clinically. This study investigates the prognostic properties of these variables, together with classical histopathological variables, in multivariate analysis in a stringently stratified material.

Original language	English
Pages (from-to)	1064-1073
Journal	Acta Obstetricia et Gynecologica Scandinavica
Volume	94
Issue number	10
DOIs	https://doi.org/10.1111/aogs.12704
Publication status	Published - 2015

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SDG 3 Good Health and Well-being

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Cancer and Oncology

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10.1111/aogs.12704

Wiley-Blackwell_Green_et_al

http://www.ncbi.nlm.nih.gov/pubmed/26123703?dopt=Abstract

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Green, R. W., Engblom, S., Baldetorp, B., Werner Hartman, L., Måsbäck, A., & Bjurberg, M. (2015). Cell proliferation, measured as flow cytometric S-phase fraction, is a strong prognostic indicator in FIGO stage I endometrioid endometrial carcinoma: a population-based study. Acta Obstetricia et Gynecologica Scandinavica, 94(10), 1064-1073. https://doi.org/10.1111/aogs.12704

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title = "Cell proliferation, measured as flow cytometric S-phase fraction, is a strong prognostic indicator in FIGO stage I endometrioid endometrial carcinoma: a population-based study.",

abstract = "In early-stage endometrial carcinoma, there is controversy regarding the prognostic value of the flow cytometric variables DNA ploidy (diploid vs. aneuploid) and S-phase fraction. In Sweden, the former is included in national guidelines despite poor scientific support and the latter is not used clinically. This study investigates the prognostic properties of these variables, together with classical histopathological variables, in multivariate analysis in a stringently stratified material.",

author = "Green, \{Rasmus W\} and Sanna Engblom and Bo Baldetorp and \{Werner Hartman\}, Linda and Anna M{\aa}sb{\"a}ck and Maria Bjurberg",

year = "2015",

doi = "10.1111/aogs.12704",

language = "English",

volume = "94",

pages = "1064--1073",

journal = "Acta Obstetricia et Gynecologica Scandinavica",

issn = "1600-0412",

publisher = "Wiley-Blackwell",

number = "10",

}

Green, RW, Engblom, S, Baldetorp, B , Werner Hartman, L, Måsbäck, A & Bjurberg, M 2015, 'Cell proliferation, measured as flow cytometric S-phase fraction, is a strong prognostic indicator in FIGO stage I endometrioid endometrial carcinoma: a population-based study.', Acta Obstetricia et Gynecologica Scandinavica, vol. 94, no. 10, pp. 1064-1073. https://doi.org/10.1111/aogs.12704

Cell proliferation, measured as flow cytometric S-phase fraction, is a strong prognostic indicator in FIGO stage I endometrioid endometrial carcinoma: a population-based study. / Green, Rasmus W; Engblom, Sanna; Baldetorp, Bo et al.
In: Acta Obstetricia et Gynecologica Scandinavica, Vol. 94, No. 10, 2015, p. 1064-1073.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Cell proliferation, measured as flow cytometric S-phase fraction, is a strong prognostic indicator in FIGO stage I endometrioid endometrial carcinoma: a population-based study.

AU - Green, Rasmus W

AU - Engblom, Sanna

AU - Baldetorp, Bo

AU - Werner Hartman, Linda

AU - Måsbäck, Anna

AU - Bjurberg, Maria

PY - 2015

Y1 - 2015

N2 - In early-stage endometrial carcinoma, there is controversy regarding the prognostic value of the flow cytometric variables DNA ploidy (diploid vs. aneuploid) and S-phase fraction. In Sweden, the former is included in national guidelines despite poor scientific support and the latter is not used clinically. This study investigates the prognostic properties of these variables, together with classical histopathological variables, in multivariate analysis in a stringently stratified material.

AB - In early-stage endometrial carcinoma, there is controversy regarding the prognostic value of the flow cytometric variables DNA ploidy (diploid vs. aneuploid) and S-phase fraction. In Sweden, the former is included in national guidelines despite poor scientific support and the latter is not used clinically. This study investigates the prognostic properties of these variables, together with classical histopathological variables, in multivariate analysis in a stringently stratified material.

UR - https://www.scopus.com/pages/publications/84941660184

U2 - 10.1111/aogs.12704

DO - 10.1111/aogs.12704

M3 - Article

C2 - 26123703

SN - 1600-0412

VL - 94

SP - 1064

EP - 1073

JO - Acta Obstetricia et Gynecologica Scandinavica

JF - Acta Obstetricia et Gynecologica Scandinavica

IS - 10

ER -

Cell proliferation, measured as flow cytometric S-phase fraction, is a strong prognostic indicator in FIGO stage I endometrioid endometrial carcinoma: a population-based study.

Abstract

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