Cerebral Mitochondrial Dysfunction and the Development of Targeted Therapeutics

Michael Karlsson

Cerebral Mitochondrial Dysfunction and the Development of Targeted Therapeutics

Mitochondrial Medicine

Research output: Thesis › Doctoral Thesis (compilation)

885 Downloads (Pure)

Original language	English
Qualification	Doctor
Awarding Institution
Supervisors/Advisors	Elmer, Eskil, Supervisor Hansson, Magnus, Supervisor
Award date	2017 Dec 8
Place of Publication	Lund
Publisher	Lund University: Faculty of Medicine
ISBN (Print)	978-91-7619-556-7
Publication status	Published - 2017

Bibliographical note

Defence details
Date: 2017-12-08
Time: 13:00
Place: Belfragesalen, BMC D15, Klinikgatan 32 i Lund
External reviewer(s)
Name: Sullivan, Patrick
Title: Professor
Affiliation: Department of Neuroscience, The Spinal Cord & Brain Injury Research Center, The University of Kentucky Chandler College of Medicine, Lexington, KY, USA
---
ISSN: 1652-8220
Lund University, Faculty of Medicine Doctoral Dissertation Series 2017:174

Subject classification (UKÄ)

Medical and Health Sciences

Access to Document

240499_1_G5_Michael K_electonic versionFinal published version, 3.45 MB

3 Article

Changes in energy metabolism due to acute rotenone-induced mitochondrial complex I dysfunction – An in vivo large animal model
Karlsson, M., Ehinger, J. K., Piel, S., Sjövall, F., Henriksnäs, J., Höglund, U., Hansson, M. J. & Elmér, E., 2016 Nov 1, In: Mitochondrion. 31, p. 56-62 7 p.
Research output: Contribution to journal › Article › peer-review
Cell-permeable succinate prodrugs bypass mitochondrial complex i deficiency
Ehinger, J. K., Piel, S., Ford, R., Karlsson, M., Sjövall, F., Frostner, E. Å., Morota, S., Taylor, R. W., Turnbull, D. M., Cornell, C., Moss, S. J., Metzsch, C., Hansson, M. J., Fliri, H. & Elmér, E., 2016 Aug 9, In: Nature Communications. 7, 12317.
Research output: Contribution to journal › Article › peer-review

Open Access
Diverse and Tissue Specific Mitochondrial Respiratory Response in A Mouse Model of Sepsis-Induced Multiple Organ Failure.
Karlsson, M., Hara, N., Morata, S., Sjövall, F., Kilbaugh, T., Hansson, M., Uchino, H. & Elmer, E., 2016, In: Shock. 45, 4, p. 404-410
Research output: Contribution to journal › Article › peer-review

Open Access
File
304 Downloads (Pure)

Cite this

@phdthesis{bcf9686796a24317a5ae02eef20117cb,

title = "Cerebral Mitochondrial Dysfunction and the Development of Targeted Therapeutics",

keywords = "mitochondria, brain, animal models, sepsis, traumatic brain injury, neuroprotection, cyclosporine",

author = "Michael Karlsson",

note = "Defence details Date: 2017-12-08 Time: 13:00 Place: Belfragesalen, BMC D15, Klinikgatan 32 i Lund External reviewer(s) Name: Sullivan, Patrick Title: Professor Affiliation: Department of Neuroscience, The Spinal Cord & Brain Injury Research Center, The University of Kentucky Chandler College of Medicine, Lexington, KY, USA --- ISSN: 1652-8220 Lund University, Faculty of Medicine Doctoral Dissertation Series 2017:174",

year = "2017",

language = "English",

isbn = "978-91-7619-556-7",

publisher = "Lund University: Faculty of Medicine",

type = "Doctoral Thesis (compilation)",

}

TY - THES

T1 - Cerebral Mitochondrial Dysfunction and the Development of Targeted Therapeutics

AU - Karlsson, Michael

N1 - Defence details Date: 2017-12-08 Time: 13:00 Place: Belfragesalen, BMC D15, Klinikgatan 32 i Lund External reviewer(s) Name: Sullivan, Patrick Title: Professor Affiliation: Department of Neuroscience, The Spinal Cord & Brain Injury Research Center, The University of Kentucky Chandler College of Medicine, Lexington, KY, USA --- ISSN: 1652-8220 Lund University, Faculty of Medicine Doctoral Dissertation Series 2017:174

PY - 2017

Y1 - 2017

KW - mitochondria

KW - brain

KW - animal models

KW - sepsis

KW - traumatic brain injury

KW - neuroprotection

KW - cyclosporine

M3 - Doctoral Thesis (compilation)

SN - 978-91-7619-556-7

PB - Lund University: Faculty of Medicine

CY - Lund

ER -

Cerebral Mitochondrial Dysfunction and the Development of Targeted Therapeutics

Bibliographical note

Subject classification (UKÄ)

Access to Document

Research output

Changes in energy metabolism due to acute rotenone-induced mitochondrial complex I dysfunction – An in vivo large animal model

Cell-permeable succinate prodrugs bypass mitochondrial complex i deficiency

Diverse and Tissue Specific Mitochondrial Respiratory Response in A Mouse Model of Sepsis-Induced Multiple Organ Failure.

Cite this