Characterization of probe contact effects on diffuse reflectance spectroscopy measurements

Nina Reistad, Mallory Mayjonade, Aylin Ahadi, Stefan Andersson-Engels

Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceedingpeer-review

Abstract

Diffuse reflectance spectroscopy (DRS) is a rapid, non-invasive optical method widely adopted to gain diagnostic information of tissue. The most flexible approach to this method is a fiber-optic contact-probe used with a spectroscopy system. A challenge of this method is that the external pressure brought by the probe can significantly affect the tissue optical properties as well as the light coupling into the probe, and thus influence the collected DRS-spectrum. In this study we investigate and characterize the effect of probe pressure on DRS-spectra obtained with a calibrated loaded-spring system used with a fiber optic probe in the range (400 – 1600) nm. A multilayer FE-model of the indentation is developed to get a better insight of the distribution of pressure and stresses inside the skin under indentation.
Original languageEnglish
Title of host publicationBioPhotonics South America (SPIE Proceedings)
PublisherSPIE
Pages953143
Number of pages8
Volume9531
DOIs
Publication statusPublished - 2015
EventJoint Meeting of the 1st SPIE Conference on Biophotonics South America (BSA) / 15th World Congress of the International-Photodynamic-Association (IPA) - Rio de Janeiro, Brazil
Duration: 2015 May 232015 May 25

Publication series

Name
Volume9531
ISSN (Print)1996-756X
ISSN (Electronic)0277-786X

Conference

ConferenceJoint Meeting of the 1st SPIE Conference on Biophotonics South America (BSA) / 15th World Congress of the International-Photodynamic-Association (IPA)
Country/TerritoryBrazil
CityRio de Janeiro
Period2015/05/232015/05/25

Subject classification (UKÄ)

  • Atom and Molecular Physics and Optics
  • Applied Mechanics

Free keywords

  • Diffuse reflectance spectroscopy
  • probe contact pressure
  • finite element simulation
  • biomechanical
  • tissue optical properties.

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