Childhood cancer survival trends in Europe: a EUROCARE Working Group study

Gemma Gatta; Riccardo Capocaccia; Charles Stiller; Peter Kaatsch; Franco Berrino; Monica Terenziani; H H Storm; T Aareleid; T Hakulinen; G Hédelin; I Tron; E Le Gall; G Launoy; J Macé-Lesech; J Faivre; G Chaplain; P-M Carli; B Lacour; C Berger; F Freycon; J Estève; L Tryggvadottir; C Allemani; P Baili; L Ciccolallo; A Micheli; M Sant,; E Taussig; E Carrani,; R De Angelis; P Roazzi; M Santaquilani; A Tavilla; F Valente; A Verdecchia; S Ferretti; p Crosignani; G Tagliabue; V Ramazzotti; M C Cercato; M Vercelli; A Orengo; V De Lisi; L Serventi; C Magnani; G Pastore; L Gafa`; R Tumino; E Paci; E Crocetti; F Langmark; A Andersen; J Rachtan; I Plesˇko; A Obsitníkova´; V Pompe-Kirn; E Ardanaz; C Moreno; J Galceran; A Torrella; R Peris-Bonet; L Barlow; Torgil Möller; G Jundt; J-M Lutz; M Usel; J W W Coebergh; M P Coleman; J A Steward; R Black; D Brewster

doi:10.1200/JCO.2005.00.554

Childhood cancer survival trends in Europe: a EUROCARE Working Group study

Gemma Gatta, Riccardo Capocaccia, Charles Stiller, Peter Kaatsch, Franco Berrino, Monica Terenziani, H H Storm, T Aareleid, T Hakulinen, G Hédelin, I Tron, E Le Gall, G Launoy, J Macé-Lesech, J Faivre, G Chaplain, P-M Carli, B Lacour, C Berger, F FreyconJ Estève, L Tryggvadottir, C Allemani, P Baili, L Ciccolallo, A Micheli, M Sant,, E Taussig, E Carrani,, R De Angelis, P Roazzi, M Santaquilani, A Tavilla, F Valente, A Verdecchia, S Ferretti, p Crosignani, G Tagliabue, V Ramazzotti, M C Cercato, M Vercelli, A Orengo, V De Lisi, L Serventi, C Magnani, G Pastore, L Gafa`, R Tumino, E Paci, E Crocetti, F Langmark, A Andersen, J Rachtan, I Plesˇko, A Obsitníkova´, V Pompe-Kirn, E Ardanaz, C Moreno, J Galceran, A Torrella, R Peris-Bonet, L Barlow, Torgil Möller, G Jundt, J-M Lutz, M Usel, J W W Coebergh, M P Coleman, J A Steward, R Black, D Brewster

Cancer Registry of Sweden

Research output: Contribution to journal › Article › peer-review

Abstract

PURPOSE: EUROCARE collected data from population-based cancer registries in 20 European countries. We used this data to compare childhood cancer survival time trends in Europe. PATIENTS AND METHODS: Survival in 44,129 children diagnosed under the age of 15 years during 1983 to 1994 was analyzed. Sex- and age-adjusted 5-year survival trends for 10 common cancers and for all cancers combined were estimated for five regions (West Germany, the United Kingdom, Eastern Europe, Nordic countries, and West and South Europe) and Europe as a whole. Europe-wide trends for 14 rare cancers were estimated. RESULTS: For all cancers combined, 5-year survival increased from 65% for diagnoses in 1983 to 1985 to 75% in 1992 to 1994. Survival improved for all individual cancers except melanoma, osteosarcoma, and thyroid carcinoma; although for retinoblastoma, chondrosarcoma, and fibrosarcoma, improvements were not significant. The most marked improvements (50% to 66%) occurred in Eastern Europe. For common cancers, the greatest improvements were for leukemia and lymphomas, with risk of dying reducing significantly by 5% to 6% per year. Survival for CNS tumors improved significantly from 57% to 65%, with risk reducing by 3% per year. Risk reduced by 4% per year for neuroblastoma and 3% per year for Wilms' tumor and rhabdomyosarcoma. The survival gap between regions reduced over the period, particularly for acute nonlymphocytic leukemia, CNS tumors, and rhabdomyosarcoma. For rare Burkitt's lymphoma, hepatoblastoma, gonadal germ cell tumors, and nasopharyngeal carcinoma, risk reductions were at least 10% per year. CONCLUSION: These gratifying improvements in survival can often be plausibly related to advances in treatment. The prevalence of European adults with a history of childhood cancer will inevitably increase.

Original language	English
Pages (from-to)	3742-3751
Journal	Journal of Clinical Oncology
Volume	23
Issue number	16
DOIs	https://doi.org/10.1200/JCO.2005.00.554
Publication status	Published - 2005
Externally published	Yes

Subject classification (UKÄ)

Cancer and Oncology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1200/JCO.2005.00.554

Cite this

Gatta, G., Capocaccia, R., Stiller, C., Kaatsch, P., Berrino, F., Terenziani, M., Storm, H. H., Aareleid, T., Hakulinen, T., Hédelin, G., Tron, I., Le Gall, E., Launoy, G., Macé-Lesech, J., Faivre, J., Chaplain, G., Carli, P.-M., Lacour, B., Berger, C., ... Brewster, D. (2005). Childhood cancer survival trends in Europe: a EUROCARE Working Group study. Journal of Clinical Oncology, 23(16), 3742-3751. https://doi.org/10.1200/JCO.2005.00.554

@article{773021a7480a4cf78d2fd4ac98422d16,

title = "Childhood cancer survival trends in Europe: a EUROCARE Working Group study",

abstract = "PURPOSE: EUROCARE collected data from population-based cancer registries in 20 European countries. We used this data to compare childhood cancer survival time trends in Europe. PATIENTS AND METHODS: Survival in 44,129 children diagnosed under the age of 15 years during 1983 to 1994 was analyzed. Sex- and age-adjusted 5-year survival trends for 10 common cancers and for all cancers combined were estimated for five regions (West Germany, the United Kingdom, Eastern Europe, Nordic countries, and West and South Europe) and Europe as a whole. Europe-wide trends for 14 rare cancers were estimated. RESULTS: For all cancers combined, 5-year survival increased from 65% for diagnoses in 1983 to 1985 to 75% in 1992 to 1994. Survival improved for all individual cancers except melanoma, osteosarcoma, and thyroid carcinoma; although for retinoblastoma, chondrosarcoma, and fibrosarcoma, improvements were not significant. The most marked improvements (50% to 66%) occurred in Eastern Europe. For common cancers, the greatest improvements were for leukemia and lymphomas, with risk of dying reducing significantly by 5% to 6% per year. Survival for CNS tumors improved significantly from 57% to 65%, with risk reducing by 3% per year. Risk reduced by 4% per year for neuroblastoma and 3% per year for Wilms' tumor and rhabdomyosarcoma. The survival gap between regions reduced over the period, particularly for acute nonlymphocytic leukemia, CNS tumors, and rhabdomyosarcoma. For rare Burkitt's lymphoma, hepatoblastoma, gonadal germ cell tumors, and nasopharyngeal carcinoma, risk reductions were at least 10% per year. CONCLUSION: These gratifying improvements in survival can often be plausibly related to advances in treatment. The prevalence of European adults with a history of childhood cancer will inevitably increase.",

author = "Gemma Gatta and Riccardo Capocaccia and Charles Stiller and Peter Kaatsch and Franco Berrino and Monica Terenziani and Storm, {H H} and T Aareleid and T Hakulinen and G H{\'e}delin and I Tron and {Le Gall}, E and G Launoy and J Mac{\'e}-Lesech and J Faivre and G Chaplain and P-M Carli and B Lacour and C Berger and F Freycon and J Est{\`e}ve and L Tryggvadottir and C Allemani and P Baili and L Ciccolallo and A Micheli and M Sant, and E Taussig and E Carrani, and {De Angelis}, R and P Roazzi and M Santaquilani and A Tavilla and F Valente and A Verdecchia and S Ferretti and p Crosignani and G Tagliabue and V Ramazzotti and Cercato, {M C} and M Vercelli and A Orengo and {De Lisi}, V and L Serventi and C Magnani and G Pastore and L Gafa` and R Tumino and E Paci and E Crocetti and F Langmark and A Andersen and J Rachtan and I Plesˇko and A Obsitn{\'i}kova´ and V Pompe-Kirn and E Ardanaz and C Moreno and J Galceran and A Torrella and R Peris-Bonet and L Barlow and Torgil M{\"o}ller and G Jundt and J-M Lutz and M Usel and Coebergh, {J W W} and Coleman, {M P} and Steward, {J A} and R Black and D Brewster",

year = "2005",

doi = "10.1200/JCO.2005.00.554",

language = "English",

volume = "23",

pages = "3742--3751",

journal = "Journal of Clinical Oncology",

issn = "1527-7755",

publisher = "American Society of Clinical Oncology",

number = "16",

}

Gatta, G, Capocaccia, R, Stiller, C, Kaatsch, P, Berrino, F, Terenziani, M, Storm, HH, Aareleid, T, Hakulinen, T, Hédelin, G, Tron, I, Le Gall, E, Launoy, G, Macé-Lesech, J, Faivre, J, Chaplain, G, Carli, P-M, Lacour, B, Berger, C, Freycon, F, Estève, J, Tryggvadottir, L, Allemani, C, Baili, P, Ciccolallo, L, Micheli, A, Sant, M, Taussig, E, Carrani, E, De Angelis, R, Roazzi, P, Santaquilani, M, Tavilla, A, Valente, F, Verdecchia, A, Ferretti, S, Crosignani, P, Tagliabue, G, Ramazzotti, V, Cercato, MC, Vercelli, M, Orengo, A, De Lisi, V, Serventi, L, Magnani, C, Pastore, G, Gafa`, L, Tumino, R, Paci, E, Crocetti, E, Langmark, F, Andersen, A, Rachtan, J, Plesˇko, I, Obsitníkova´, A, Pompe-Kirn, V, Ardanaz, E, Moreno, C, Galceran, J, Torrella, A, Peris-Bonet, R, Barlow, L, Möller, T, Jundt, G, Lutz, J-M, Usel, M, Coebergh, JWW, Coleman, MP, Steward, JA, Black, R & Brewster, D 2005, 'Childhood cancer survival trends in Europe: a EUROCARE Working Group study', Journal of Clinical Oncology, vol. 23, no. 16, pp. 3742-3751. https://doi.org/10.1200/JCO.2005.00.554

TY - JOUR

T1 - Childhood cancer survival trends in Europe: a EUROCARE Working Group study

AU - Gatta, Gemma

AU - Capocaccia, Riccardo

AU - Stiller, Charles

AU - Kaatsch, Peter

AU - Berrino, Franco

AU - Terenziani, Monica

AU - Storm, H H

AU - Aareleid, T

AU - Hakulinen, T

AU - Hédelin, G

AU - Tron, I

AU - Le Gall, E

AU - Launoy, G

AU - Macé-Lesech, J

AU - Faivre, J

AU - Chaplain, G

AU - Carli, P-M

AU - Lacour, B

AU - Berger, C

AU - Freycon, F

AU - Estève, J

AU - Tryggvadottir, L

AU - Allemani, C

AU - Baili, P

AU - Ciccolallo, L

AU - Micheli, A

AU - Sant,, M

AU - Taussig, E

AU - Carrani,, E

AU - De Angelis, R

AU - Roazzi, P

AU - Santaquilani, M

AU - Tavilla, A

AU - Valente, F

AU - Verdecchia, A

AU - Ferretti, S

AU - Crosignani, p

AU - Tagliabue, G

AU - Ramazzotti, V

AU - Cercato, M C

AU - Vercelli, M

AU - Orengo, A

AU - De Lisi, V

AU - Serventi, L

AU - Magnani, C

AU - Pastore, G

AU - Gafa`, L

AU - Tumino, R

AU - Paci, E

AU - Crocetti, E

AU - Langmark, F

AU - Andersen, A

AU - Rachtan, J

AU - Plesˇko, I

AU - Obsitníkova´, A

AU - Pompe-Kirn, V

AU - Ardanaz, E

AU - Moreno, C

AU - Galceran, J

AU - Torrella, A

AU - Peris-Bonet, R

AU - Barlow, L

AU - Möller, Torgil

AU - Jundt, G

AU - Lutz, J-M

AU - Usel, M

AU - Coebergh, J W W

AU - Coleman, M P

AU - Steward, J A

AU - Black, R

AU - Brewster, D

PY - 2005

Y1 - 2005

N2 - PURPOSE: EUROCARE collected data from population-based cancer registries in 20 European countries. We used this data to compare childhood cancer survival time trends in Europe. PATIENTS AND METHODS: Survival in 44,129 children diagnosed under the age of 15 years during 1983 to 1994 was analyzed. Sex- and age-adjusted 5-year survival trends for 10 common cancers and for all cancers combined were estimated for five regions (West Germany, the United Kingdom, Eastern Europe, Nordic countries, and West and South Europe) and Europe as a whole. Europe-wide trends for 14 rare cancers were estimated. RESULTS: For all cancers combined, 5-year survival increased from 65% for diagnoses in 1983 to 1985 to 75% in 1992 to 1994. Survival improved for all individual cancers except melanoma, osteosarcoma, and thyroid carcinoma; although for retinoblastoma, chondrosarcoma, and fibrosarcoma, improvements were not significant. The most marked improvements (50% to 66%) occurred in Eastern Europe. For common cancers, the greatest improvements were for leukemia and lymphomas, with risk of dying reducing significantly by 5% to 6% per year. Survival for CNS tumors improved significantly from 57% to 65%, with risk reducing by 3% per year. Risk reduced by 4% per year for neuroblastoma and 3% per year for Wilms' tumor and rhabdomyosarcoma. The survival gap between regions reduced over the period, particularly for acute nonlymphocytic leukemia, CNS tumors, and rhabdomyosarcoma. For rare Burkitt's lymphoma, hepatoblastoma, gonadal germ cell tumors, and nasopharyngeal carcinoma, risk reductions were at least 10% per year. CONCLUSION: These gratifying improvements in survival can often be plausibly related to advances in treatment. The prevalence of European adults with a history of childhood cancer will inevitably increase.

AB - PURPOSE: EUROCARE collected data from population-based cancer registries in 20 European countries. We used this data to compare childhood cancer survival time trends in Europe. PATIENTS AND METHODS: Survival in 44,129 children diagnosed under the age of 15 years during 1983 to 1994 was analyzed. Sex- and age-adjusted 5-year survival trends for 10 common cancers and for all cancers combined were estimated for five regions (West Germany, the United Kingdom, Eastern Europe, Nordic countries, and West and South Europe) and Europe as a whole. Europe-wide trends for 14 rare cancers were estimated. RESULTS: For all cancers combined, 5-year survival increased from 65% for diagnoses in 1983 to 1985 to 75% in 1992 to 1994. Survival improved for all individual cancers except melanoma, osteosarcoma, and thyroid carcinoma; although for retinoblastoma, chondrosarcoma, and fibrosarcoma, improvements were not significant. The most marked improvements (50% to 66%) occurred in Eastern Europe. For common cancers, the greatest improvements were for leukemia and lymphomas, with risk of dying reducing significantly by 5% to 6% per year. Survival for CNS tumors improved significantly from 57% to 65%, with risk reducing by 3% per year. Risk reduced by 4% per year for neuroblastoma and 3% per year for Wilms' tumor and rhabdomyosarcoma. The survival gap between regions reduced over the period, particularly for acute nonlymphocytic leukemia, CNS tumors, and rhabdomyosarcoma. For rare Burkitt's lymphoma, hepatoblastoma, gonadal germ cell tumors, and nasopharyngeal carcinoma, risk reductions were at least 10% per year. CONCLUSION: These gratifying improvements in survival can often be plausibly related to advances in treatment. The prevalence of European adults with a history of childhood cancer will inevitably increase.

U2 - 10.1200/JCO.2005.00.554

DO - 10.1200/JCO.2005.00.554

M3 - Article

SN - 1527-7755

VL - 23

SP - 3742

EP - 3751

JO - Journal of Clinical Oncology

JF - Journal of Clinical Oncology

IS - 16

ER -

Childhood cancer survival trends in Europe: a EUROCARE Working Group study

Abstract

Subject classification (UKÄ)

UN SDGs

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