Chip Based Electroanalytical Systems for Cell Analysis

Christer Spegel, Arto Heiskanen, Lars Henrik Skjolding, Jenny Emnéus

Research output: Contribution to journalReview articlepeer-review

Abstract

This review with 239 references has as its aim to give the reader an introduction to the kinds of methods used for developing microchip based electrode systems as well as to cover the existing literature on electroanalytical systems where microchips play a crucial role for “none-destructive” measurements of processes related to living cells, i.e., systems without lysing the cells. The focus is on chip based amperometric and impedimetric cell analysis systems where measurements utilizing solely carbon fibre microelectrodes (CFME) and other non-chip electrode formats, such as CFME for exocytosis studies and scanning electrochemical microscopy (SECM) studies of living cells have been omitted. Included is also a discussion about some future and emerging nano tools and considerations that might have an impact on the future of “non-destructive” chip based electroanalysis of living cells.
Original languageEnglish
Pages (from-to)680-702
JournalElectroanalysis
Volume20
Issue number6
DOIs
Publication statusPublished - 2008

Bibliographical note

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Analytical Chemistry (S/LTH) (011001004), Solid State Physics (011013006)

Subject classification (UKÄ)

  • Condensed Matter Physics (including Material Physics, Nano Physics)
  • Analytical Chemistry

Free keywords

  • non-destructive cell analysis
  • nanoelectrode
  • amperometry
  • microchip
  • cell impedance

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