Chitosan-DNA Particles for DNA Delivery: Effect of Chitosan Molecular Weight on Formation and Release Characteristics

M. C. Moran, T. Laranjeira, A. Ribeiro, M. G. Miguel, Björn Lindman

Research output: Contribution to journalArticlepeer-review

9 Citations (SciVal)

Abstract

Novel DNA-chitosan particles were prepared based on associative phase separation and interfacial diffusion. These particles formed at water/water emulsion type interfaces were characterized with respect to several properties including stability, DNA conformational state, and entrapment and release of DNA. In particular it was found that the chitosan molecular weight is a good controlling parameter.
Original languageEnglish
Pages (from-to)1494-1499
JournalJournal of Dispersion Science and Technology
Volume30
Issue number10
DOIs
Publication statusPublished - 2009

Subject classification (UKÄ)

  • Physical Chemistry

Keywords

  • DNA release
  • Chitosan
  • DNA gel particles

Fingerprint

Dive into the research topics of 'Chitosan-DNA Particles for DNA Delivery: Effect of Chitosan Molecular Weight on Formation and Release Characteristics'. Together they form a unique fingerprint.

Cite this