Ciprofloxacin does not inhibit mitochondrial functions but other antiboitics do

K. Riesbeck, A. Bredberg, A. Forsgren

Research output: Contribution to journalArticlepeer-review

Abstract

At clinical concentrations, ciprofloxacin did not inhibit mitochondrial DNA replication, oxidative phosphorylation, protein synthesis, or mitochondrial mass (transmembrane potential). No difference in supercoiled forms of DNA was observed. The tetracyclines and chloramphenicol inhibited protein synthesis at clinically achievable concentrations, while rifampin, fusidic acid, and clindamycin did not.

Original languageEnglish
Pages (from-to)167-169
JournalAntimicrobial Agents and Chemotherapy
Volume34
Issue number1
DOIs
Publication statusPublished - 1990 Jan 1

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