Circulating CD40+ and CD86+ B Cell Subsets Demonstrate Opposing Associations With Risk of Stroke.

Polyxeni Mantani; Irena Ljungcrantz; Linda Andersson; Ragnar Alm; Bo Hedblad; Harry Björkbacka; Jan Nilsson; Gunilla Nordin Fredrikson

doi:10.1161/ATVBAHA.113.302667

Circulating CD40+ and CD86+ B Cell Subsets Demonstrate Opposing Associations With Risk of Stroke.

Polyxeni Mantani, Irena Ljungcrantz, Linda Andersson, Ragnar Alm, Bo Hedblad, Harry Björkbacka, Jan Nilsson, Gunilla Nordin Fredrikson

Research output: Contribution to journal › Article › peer-review

Abstract

Accumulating evidence shows that immune cells play an important role in atherosclerosis. Most attention has focused on the role of different T cell subsets, whereas the possible involvement of B cells has been less studied. In this study, we assessed the association of 2 different B cell subsets, CD19(+)CD40(+) and CD19(+)CD86(+) B cells, with risk for development of acute cardiovascular events.

Original language	English
Pages (from-to)	211
Journal	Arteriosclerosis, Thrombosis and Vascular Biology
Volume	34
Issue number	1
DOIs	https://doi.org/10.1161/ATVBAHA.113.302667
Publication status	Published - 2014

Subject classification (UKÄ)

Cardiology and Cardiovascular Disease

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10.1161/ATVBAHA.113.302667

http://www.ncbi.nlm.nih.gov/pubmed/24202305?dopt=Abstract

1 Doctoral Thesis (compilation)

IL-25 and B cells in atherosclerosis
Mantani, P., 2014, Experimental Cardiovascular Research Unit, Lund University. 173 p.
Research output: Thesis › Doctoral Thesis (compilation)

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abstract = "Accumulating evidence shows that immune cells play an important role in atherosclerosis. Most attention has focused on the role of different T cell subsets, whereas the possible involvement of B cells has been less studied. In this study, we assessed the association of 2 different B cell subsets, CD19(+)CD40(+) and CD19(+)CD86(+) B cells, with risk for development of acute cardiovascular events.",

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AU - Mantani, Polyxeni

AU - Ljungcrantz, Irena

AU - Andersson, Linda

AU - Alm, Ragnar

AU - Hedblad, Bo

AU - Björkbacka, Harry

AU - Nilsson, Jan

AU - Nordin Fredrikson, Gunilla

PY - 2014

Y1 - 2014

N2 - Accumulating evidence shows that immune cells play an important role in atherosclerosis. Most attention has focused on the role of different T cell subsets, whereas the possible involvement of B cells has been less studied. In this study, we assessed the association of 2 different B cell subsets, CD19(+)CD40(+) and CD19(+)CD86(+) B cells, with risk for development of acute cardiovascular events.

AB - Accumulating evidence shows that immune cells play an important role in atherosclerosis. Most attention has focused on the role of different T cell subsets, whereas the possible involvement of B cells has been less studied. In this study, we assessed the association of 2 different B cell subsets, CD19(+)CD40(+) and CD19(+)CD86(+) B cells, with risk for development of acute cardiovascular events.

U2 - 10.1161/ATVBAHA.113.302667

DO - 10.1161/ATVBAHA.113.302667

M3 - Article

C2 - 24202305

SN - 1524-4636

VL - 34

SP - 211

JO - Arteriosclerosis, Thrombosis and Vascular Biology

JF - Arteriosclerosis, Thrombosis and Vascular Biology

IS - 1

ER -

Circulating CD40+ and CD86+ B Cell Subsets Demonstrate Opposing Associations With Risk of Stroke.

Abstract

Subject classification (UKÄ)

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Research output

IL-25 and B cells in atherosclerosis

Cite this