Circulating complexes between tumour necrosis factor-alpha and etanercept predict long-term efficacy of etanercept in juvenile idiopathic arthritis.

Robin Kahn; Elisabet Berthold; Birgitta Gullstrand; Tobias Schmidt; Fredrik Kahn; Pierre Geborek; Tore Saxne; Anders Bengtsson; Bengt Månsson

doi:10.1111/apa.13319

Circulating complexes between tumour necrosis factor-alpha and etanercept predict long-term efficacy of etanercept in juvenile idiopathic arthritis.

Robin Kahn, Elisabet Berthold, Birgitta Gullstrand, Tobias Schmidt, Fredrik Kahn, Pierre Geborek, Tore Saxne, Anders Bengtsson, Bengt Månsson

Research output: Contribution to journal › Article › peer-review

Abstract

The relationship between tumour necrosis factor-alpha (TNF-α) and drug survival had not been studied in juvenile idiopathic arthritis (JIA) and there were no laboratory tests to predict the long-term efficacy of biological drugs for JIA. We studied if serum levels of TNF-α, free or bound to etanercept, could predict long-term efficacy of etanercept in children with JIA.

Original language	English
Pages (from-to)	427-432
Journal	Acta paediatrica
Volume	105
Issue number	4
Early online date	2015 Dec 27
DOIs	https://doi.org/10.1111/apa.13319
Publication status	Published - 2016

Subject classification (UKÄ)

Rheumatology and Autoimmunity
Pediatrics

Access to Document

10.1111/apa.13319

http://www.ncbi.nlm.nih.gov/pubmed/26707699?dopt=Abstract

Cite this

@article{fb3356fd873349f98165738293d5b3b2,

title = "Circulating complexes between tumour necrosis factor-alpha and etanercept predict long-term efficacy of etanercept in juvenile idiopathic arthritis.",

abstract = "The relationship between tumour necrosis factor-alpha (TNF-α) and drug survival had not been studied in juvenile idiopathic arthritis (JIA) and there were no laboratory tests to predict the long-term efficacy of biological drugs for JIA. We studied if serum levels of TNF-α, free or bound to etanercept, could predict long-term efficacy of etanercept in children with JIA.",

author = "Robin Kahn and Elisabet Berthold and Birgitta Gullstrand and Tobias Schmidt and Fredrik Kahn and Pierre Geborek and Tore Saxne and Anders Bengtsson and Bengt M{\aa}nsson",

year = "2016",

doi = "10.1111/apa.13319",

language = "English",

volume = "105",

pages = "427--432",

journal = "Acta P{\ae}diatrica",

issn = "1651-2227",

publisher = "Wiley-Blackwell",

number = "4",

}

TY - JOUR

T1 - Circulating complexes between tumour necrosis factor-alpha and etanercept predict long-term efficacy of etanercept in juvenile idiopathic arthritis.

AU - Kahn, Robin

AU - Berthold, Elisabet

AU - Gullstrand, Birgitta

AU - Schmidt, Tobias

AU - Kahn, Fredrik

AU - Geborek, Pierre

AU - Saxne, Tore

AU - Bengtsson, Anders

AU - Månsson, Bengt

PY - 2016

Y1 - 2016

N2 - The relationship between tumour necrosis factor-alpha (TNF-α) and drug survival had not been studied in juvenile idiopathic arthritis (JIA) and there were no laboratory tests to predict the long-term efficacy of biological drugs for JIA. We studied if serum levels of TNF-α, free or bound to etanercept, could predict long-term efficacy of etanercept in children with JIA.

AB - The relationship between tumour necrosis factor-alpha (TNF-α) and drug survival had not been studied in juvenile idiopathic arthritis (JIA) and there were no laboratory tests to predict the long-term efficacy of biological drugs for JIA. We studied if serum levels of TNF-α, free or bound to etanercept, could predict long-term efficacy of etanercept in children with JIA.

U2 - 10.1111/apa.13319

DO - 10.1111/apa.13319

M3 - Article

C2 - 26707699

VL - 105

SP - 427

EP - 432

JO - Acta Pædiatrica

JF - Acta Pædiatrica

SN - 1651-2227

IS - 4

ER -

Circulating complexes between tumour necrosis factor-alpha and etanercept predict long-term efficacy of etanercept in juvenile idiopathic arthritis.

Abstract

Subject classification (UKÄ)

Access to Document

Fingerprint

Cite this