Circulating cytokines reflect the expression of pro-inflammatory cytokines in atherosclerotic plaques.

Andreas Edsfeldt; Helena Grufman; Giuseppe Asciutto; Mihaela Nitulescu; Ana Persson; Marie MN Nilsson; Jan Nilsson; Isabel Goncalves

doi:10.1016/j.atherosclerosis.2015.05.019

Circulating cytokines reflect the expression of pro-inflammatory cytokines in atherosclerotic plaques.

Andreas Edsfeldt, Helena Grufman, Giuseppe Asciutto, Mihaela Nitulescu, Ana Persson, Marie MN Nilsson, Jan Nilsson, Isabel Goncalves

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Abstract

Inflammation is a key factor in the development of plaque rupture and acute cardiovascular events. Although imaging techniques can be used to identify vulnerable atherosclerotic plaques, we are lacking non-invasive methods, such as plasma markers of plaque inflammation that could help to identify presence of vulnerable plaques. The aim of the present study was to investigate whether increased plasma levels of pro-inflammatory cytokines reflects inflammatory activity within atherosclerotic plaques.

Original language	English
Pages (from-to)	443-449
Journal	Atherosclerosis
Volume	241
Issue number	2
DOIs	https://doi.org/10.1016/j.atherosclerosis.2015.05.019
Publication status	Published - 2015

Subject classification (UKÄ)

Cardiology and Cardiovascular Disease

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10.1016/j.atherosclerosis.2015.05.019

Elsevier_Edsfeldt_et_al

http://www.ncbi.nlm.nih.gov/pubmed/26074318?dopt=Abstract

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title = "Circulating cytokines reflect the expression of pro-inflammatory cytokines in atherosclerotic plaques.",

abstract = "Inflammation is a key factor in the development of plaque rupture and acute cardiovascular events. Although imaging techniques can be used to identify vulnerable atherosclerotic plaques, we are lacking non-invasive methods, such as plasma markers of plaque inflammation that could help to identify presence of vulnerable plaques. The aim of the present study was to investigate whether increased plasma levels of pro-inflammatory cytokines reflects inflammatory activity within atherosclerotic plaques.",

author = "Andreas Edsfeldt and Helena Grufman and Giuseppe Asciutto and Mihaela Nitulescu and Ana Persson and Nilsson, {Marie MN} and Jan Nilsson and Isabel Goncalves",

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doi = "10.1016/j.atherosclerosis.2015.05.019",

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T1 - Circulating cytokines reflect the expression of pro-inflammatory cytokines in atherosclerotic plaques.

AU - Edsfeldt, Andreas

AU - Grufman, Helena

AU - Asciutto, Giuseppe

AU - Nitulescu, Mihaela

AU - Persson, Ana

AU - Nilsson, Marie MN

AU - Nilsson, Jan

AU - Goncalves, Isabel

PY - 2015

Y1 - 2015

N2 - Inflammation is a key factor in the development of plaque rupture and acute cardiovascular events. Although imaging techniques can be used to identify vulnerable atherosclerotic plaques, we are lacking non-invasive methods, such as plasma markers of plaque inflammation that could help to identify presence of vulnerable plaques. The aim of the present study was to investigate whether increased plasma levels of pro-inflammatory cytokines reflects inflammatory activity within atherosclerotic plaques.

AB - Inflammation is a key factor in the development of plaque rupture and acute cardiovascular events. Although imaging techniques can be used to identify vulnerable atherosclerotic plaques, we are lacking non-invasive methods, such as plasma markers of plaque inflammation that could help to identify presence of vulnerable plaques. The aim of the present study was to investigate whether increased plasma levels of pro-inflammatory cytokines reflects inflammatory activity within atherosclerotic plaques.

U2 - 10.1016/j.atherosclerosis.2015.05.019

DO - 10.1016/j.atherosclerosis.2015.05.019

M3 - Article

C2 - 26074318

SN - 1879-1484

VL - 241

SP - 443

EP - 449

JO - Atherosclerosis

JF - Atherosclerosis

IS - 2

ER -

Circulating cytokines reflect the expression of pro-inflammatory cytokines in atherosclerotic plaques.

Abstract

Subject classification (UKÄ)

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