Circulation stabilizing therapy and pulmonary high-resolution computed tomography in a porcine brain-dead model.

Gracijela Bozovic; Stig Steen; Trygve Sjöberg; C Schaefer-Prokop; J Verschakelen; Qiuming Liao; Peter Höglund; Roger Siemund; Isabella Björkman-Burtscher

doi:10.1111/aas.12595

Circulation stabilizing therapy and pulmonary high-resolution computed tomography in a porcine brain-dead model.

Gracijela Bozovic, Stig Steen, Trygve Sjöberg, C Schaefer-Prokop, J Verschakelen, Qiuming Liao, Peter Höglund, Roger Siemund, Isabella Björkman-Burtscher

Research output: Contribution to journal › Article › peer-review

Abstract

Currently 80% of donor lungs are not accepted for transplantation, often due to fluid overload. Our aim was to investigate if forced fluid infusion may be replaced by a new pharmacological therapy to stabilize circulation after brain death in an animal model, and to assess therapy effects on lung function and morphology trough blood gas parameters and state-of-the-art High-resolution CT (HRCT).

Original language	English
Pages (from-to)	93-102
Journal	Acta Anaesthesiologica Scandinavica
Volume	60
Issue number	1
DOIs	https://doi.org/10.1111/aas.12595
Publication status	Published - 2016

Subject classification (UKÄ)

Anesthesiology and Intensive Care

Access to Document

10.1111/aas.12595

http://www.ncbi.nlm.nih.gov/pubmed/26251260?dopt=Abstract

1 Doctoral Thesis (compilation)

Imaging in Lung Transplantation. Evaluation and Imaging of the Lung in Organ Donors.
Bozovic, G., 2016, Lund: Lund University: Faculty of Medicine. 109 p.
Research output: Thesis › Doctoral Thesis (compilation)

Open Access
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Cite this

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title = "Circulation stabilizing therapy and pulmonary high-resolution computed tomography in a porcine brain-dead model.",

abstract = "Currently 80% of donor lungs are not accepted for transplantation, often due to fluid overload. Our aim was to investigate if forced fluid infusion may be replaced by a new pharmacological therapy to stabilize circulation after brain death in an animal model, and to assess therapy effects on lung function and morphology trough blood gas parameters and state-of-the-art High-resolution CT (HRCT).",

author = "Gracijela Bozovic and Stig Steen and Trygve Sj{\"o}berg and C Schaefer-Prokop and J Verschakelen and Qiuming Liao and Peter H{\"o}glund and Roger Siemund and Isabella Bj{\"o}rkman-Burtscher",

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AU - Bozovic, Gracijela

AU - Steen, Stig

AU - Sjöberg, Trygve

AU - Schaefer-Prokop, C

AU - Verschakelen, J

AU - Liao, Qiuming

AU - Höglund, Peter

AU - Siemund, Roger

AU - Björkman-Burtscher, Isabella

PY - 2016

Y1 - 2016

N2 - Currently 80% of donor lungs are not accepted for transplantation, often due to fluid overload. Our aim was to investigate if forced fluid infusion may be replaced by a new pharmacological therapy to stabilize circulation after brain death in an animal model, and to assess therapy effects on lung function and morphology trough blood gas parameters and state-of-the-art High-resolution CT (HRCT).

AB - Currently 80% of donor lungs are not accepted for transplantation, often due to fluid overload. Our aim was to investigate if forced fluid infusion may be replaced by a new pharmacological therapy to stabilize circulation after brain death in an animal model, and to assess therapy effects on lung function and morphology trough blood gas parameters and state-of-the-art High-resolution CT (HRCT).

U2 - 10.1111/aas.12595

DO - 10.1111/aas.12595

M3 - Article

C2 - 26251260

SN - 0001-5172

VL - 60

SP - 93

EP - 102

JO - Acta Anaesthesiologica Scandinavica

JF - Acta Anaesthesiologica Scandinavica

IS - 1

ER -

Circulation stabilizing therapy and pulmonary high-resolution computed tomography in a porcine brain-dead model.

Abstract

Subject classification (UKÄ)

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Research output

Imaging in Lung Transplantation. Evaluation and Imaging of the Lung in Organ Donors.

Cite this