Clinical course in synovial sarcoma: A Scandinavian sarcoma group study of 104 patients

Björn T. Skytting; Henrik C.F. Bauer; Roland Perfekt; Riika Huuhtanen; Thor A. Alvegârd; Örjan Berlin; Pelle Gustafson; Ragnhild Klepp; Richard Löfvenberg; Gunnar Seter; Clement S. Trovik; Ola Wahlström

doi:10.3109/17453679908997839

Clinical course in synovial sarcoma: A Scandinavian sarcoma group study of 104 patients

Björn T. Skytting, Henrik C.F. Bauer, Roland Perfekt, Riika Huuhtanen, Thor A. Alvegârd, Örjan Berlin, Pelle Gustafson, Ragnhild Klepp, Richard Löfvenberg, Gunnar Seter, Clement S. Trovik, Ola Wahlström

Rheumatology

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Abstract

We analyzed treatment and outcome in 104 Scandinavian patients with synovial sarcoma in the extremities or trunk wall, diagnosed between 1986 and 1994. Only surgically treated patients without metastases at diagnosis were included. Median follow-up of survivors was 6 (3-11) years. 34 patients developed metastases. The overall 5- and 7-year survival rates were 0.76 (95% Cl 0.66-0.83) and 0.69 (0.58-0.78), respectively. Large tumor size and amputation were significantly associated with impaired metastasis-free survival. Patients with local recurrence had a higher risk of metastases following the local event. Local excision with inadequate margin was associated with a higher risk of local recurrence.

Original language	English
Pages (from-to)	536-542
Journal	Acta Orthopaedica Scandinavica
Volume	70
Issue number	6
DOIs	https://doi.org/10.3109/17453679908997839
Publication status	Published - 1999

Subject classification (UKÄ)

Orthopedics
Cancer and Oncology

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title = "Clinical course in synovial sarcoma: A Scandinavian sarcoma group study of 104 patients",

abstract = "We analyzed treatment and outcome in 104 Scandinavian patients with synovial sarcoma in the extremities or trunk wall, diagnosed between 1986 and 1994. Only surgically treated patients without metastases at diagnosis were included. Median follow-up of survivors was 6 (3-11) years. 34 patients developed metastases. The overall 5- and 7-year survival rates were 0.76 (95% Cl 0.66-0.83) and 0.69 (0.58-0.78), respectively. Large tumor size and amputation were significantly associated with impaired metastasis-free survival. Patients with local recurrence had a higher risk of metastases following the local event. Local excision with inadequate margin was associated with a higher risk of local recurrence.",

author = "Skytting, {Bj{\"o}rn T.} and Bauer, {Henrik C.F.} and Roland Perfekt and Riika Huuhtanen and Alveg{\^a}rd, {Thor A.} and {\"O}rjan Berlin and Pelle Gustafson and Ragnhild Klepp and Richard L{\"o}fvenberg and Gunnar Seter and Trovik, {Clement S.} and Ola Wahlstr{\"o}m",

year = "1999",

doi = "10.3109/17453679908997839",

language = "English",

volume = "70",

pages = "536--542",

journal = "Acta Orthopaedica",

issn = "1745-3682",

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T1 - Clinical course in synovial sarcoma

T2 - A Scandinavian sarcoma group study of 104 patients

AU - Skytting, Björn T.

AU - Bauer, Henrik C.F.

AU - Perfekt, Roland

AU - Huuhtanen, Riika

AU - Alvegârd, Thor A.

AU - Berlin, Örjan

AU - Gustafson, Pelle

AU - Klepp, Ragnhild

AU - Löfvenberg, Richard

AU - Seter, Gunnar

AU - Trovik, Clement S.

AU - Wahlström, Ola

PY - 1999

Y1 - 1999

N2 - We analyzed treatment and outcome in 104 Scandinavian patients with synovial sarcoma in the extremities or trunk wall, diagnosed between 1986 and 1994. Only surgically treated patients without metastases at diagnosis were included. Median follow-up of survivors was 6 (3-11) years. 34 patients developed metastases. The overall 5- and 7-year survival rates were 0.76 (95% Cl 0.66-0.83) and 0.69 (0.58-0.78), respectively. Large tumor size and amputation were significantly associated with impaired metastasis-free survival. Patients with local recurrence had a higher risk of metastases following the local event. Local excision with inadequate margin was associated with a higher risk of local recurrence.

AB - We analyzed treatment and outcome in 104 Scandinavian patients with synovial sarcoma in the extremities or trunk wall, diagnosed between 1986 and 1994. Only surgically treated patients without metastases at diagnosis were included. Median follow-up of survivors was 6 (3-11) years. 34 patients developed metastases. The overall 5- and 7-year survival rates were 0.76 (95% Cl 0.66-0.83) and 0.69 (0.58-0.78), respectively. Large tumor size and amputation were significantly associated with impaired metastasis-free survival. Patients with local recurrence had a higher risk of metastases following the local event. Local excision with inadequate margin was associated with a higher risk of local recurrence.

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JO - Acta Orthopaedica

JF - Acta Orthopaedica

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IS - 6

ER -

Clinical course in synovial sarcoma: A Scandinavian sarcoma group study of 104 patients

Abstract

Subject classification (UKÄ)

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