Common variation at PPARGC1A/B and change in body composition and metabolic traits following preventive interventions: the Diabetes Prevention Program.

Paul Franks, Costas A Christophi, Kathleen A Jablonski, Liana K Billings, Linda M Delahanty, Edward S Horton, William C Knowler, Jose C Florez

Research output: Contribution to journalArticlepeer-review

22 Citations (SciVal)

Abstract

PPARGC1A and PPARGCB encode transcriptional coactivators that regulate numerous metabolic processes. We tested associations and treatment (i.e. metformin or lifestyle modification) interactions with metabolic traits in the Diabetes Prevention Program, a randomised controlled trial in persons at high risk of type 2 diabetes.
Original languageEnglish
Pages (from-to)485-490
JournalDiabetologia
Volume57
Issue number3
DOIs
Publication statusPublished - 2014

Subject classification (UKÄ)

  • Endocrinology and Diabetes

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