Comparison between transcranial Doppler and coulter counter for detection of lipid micro embolization from mediastinal shed blood reinfusion during cardiac surgery.

Atli Eyjolfsson, Faleh Alrashidi, Magnus Dencker, Sara Scicluna, Björn Brondén, Bansi Koul, Henrik Bjursten

Research output: Contribution to journalArticlepeer-review

Abstract

INTRODUCTION: Lipid micro embolization (LME) from re-transfused shed blood has been postulated to be a potential reason for short- and long-term cognitive dysfunction after cardiac surgery. The purpose of this investigation was to evaluate if transcranial Doppler (TCD) has the capacity to detect LME. METHODS: Thirteen patients undergoing cardiopulmonary bypass surgery were investigated. Each patient's cerebral circulation was monitored with transcranial Doppler during the first two minutes after re-transfusion of shed blood and blood was simultaneously sampled and characterised by a Coulter counter. RESULTS: Strong correlation was found between embolic loads, as measured by transcranial Doppler and Coulter counter (r=0.79, P<0.005). CONCLUSIONS: This pilot study shows that non-invasive monitoring by transcranial Doppler could be a potential tool to monitor LME during cardiopulmonary bypass surgery.
Original languageEnglish
Pages (from-to)519-523
JournalPerfusion
Volume26
Issue number5
DOIs
Publication statusPublished - 2011

Subject classification (UKÄ)

  • Surgery
  • Cardiac and Cardiovascular Systems

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