Complete Genome Sequence of an Antimicrobial-Producing Bacillus velezensis Sam8H1 Isolate from the Makgadikgadi Saltpans of Botswana

Gorata Modikwe; Lokeshwaran Manoharan; Gomolemo Mabutho; Kebaneilwe Lebani; Lesedi Lebogang; Nerve Zhou; Julie C. Dunning Hotopp

doi:10.1128/MRA.00175-21

Complete Genome Sequence of an Antimicrobial-Producing Bacillus velezensis Sam8H1 Isolate from the Makgadikgadi Saltpans of Botswana

Gorata Modikwe, Lokeshwaran Manoharan, Gomolemo Mabutho, Kebaneilwe Lebani, Lesedi Lebogang, Nerve Zhou, Julie C. Dunning Hotopp (Editor)

Research output: Contribution to journal › Article › peer-review

Abstract

The global antimicrobial drug resistance crisis requires urgency in searching for more effective broad-spectrum antimicrobial drugs. Here, we present a complete circular genome sequence and a plasmid of an antimicrobial-producing isolate, Bacillus velezensis strain Sam8H1, from the Makgadikgadi saltpans in Botswana. Bioinformatic analyses revealed 12 putative secondary metabolite biosynthetic gene clusters important for genome-guided drug discovery studies.

Original language	English
Article number	e00175-21
Journal	Microbiology Resource Announcements
Volume	10
Issue number	17
DOIs	https://doi.org/10.1128/MRA.00175-21
Publication status	Published - 2021 Apr 29

Subject classification (UKÄ)

Microbiology in the Medical Area
Medical Genetics and Genomics (including Gene Therapy)

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10.1128/MRA.00175-21Licence: CC BY

National Bioinformatics Infrastructure Sweden
Ahrén, D. (Manager), Ringnér, M. (Manager), Levander, F. (Manager), Manoharan, L. (Manager), Oskolkov, N. (Manager), Vasquez, L. J. A. (Manager), Pyl, P. T. (Manager), Agarwal, P. (Manager), Li, Y. (Manager), Volpe, M. (Manager) & Kozjek, K. (Manager)
Department of Biology
Infrastructure

Cite this

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title = "Complete Genome Sequence of an Antimicrobial-Producing Bacillus velezensis Sam8H1 Isolate from the Makgadikgadi Saltpans of Botswana",

abstract = "The global antimicrobial drug resistance crisis requires urgency in searching for more effective broad-spectrum antimicrobial drugs. Here, we present a complete circular genome sequence and a plasmid of an antimicrobial-producing isolate, Bacillus velezensis strain Sam8H1, from the Makgadikgadi saltpans in Botswana. Bioinformatic analyses revealed 12 putative secondary metabolite biosynthetic gene clusters important for genome-guided drug discovery studies.",

author = "Gorata Modikwe and Lokeshwaran Manoharan and Gomolemo Mabutho and Kebaneilwe Lebani and Lesedi Lebogang and Nerve Zhou and {Dunning Hotopp}, {Julie C.}",

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AU - Mabutho, Gomolemo

AU - Lebani, Kebaneilwe

AU - Lebogang, Lesedi

AU - Zhou, Nerve

A2 - Dunning Hotopp, Julie C.

PY - 2021/4/29

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AB - The global antimicrobial drug resistance crisis requires urgency in searching for more effective broad-spectrum antimicrobial drugs. Here, we present a complete circular genome sequence and a plasmid of an antimicrobial-producing isolate, Bacillus velezensis strain Sam8H1, from the Makgadikgadi saltpans in Botswana. Bioinformatic analyses revealed 12 putative secondary metabolite biosynthetic gene clusters important for genome-guided drug discovery studies.

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DO - 10.1128/MRA.00175-21

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SN - 2576-098X

VL - 10

JO - Microbiology Resource Announcements

JF - Microbiology Resource Announcements

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Complete Genome Sequence of an Antimicrobial-Producing Bacillus velezensis Sam8H1 Isolate from the Makgadikgadi Saltpans of Botswana

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National Bioinformatics Infrastructure Sweden

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