Composite Material Based on Macroporous Polyaniline and Osmium Redox Complex for Biosensor Development

Riccarda Antiochia, Franco Mazzei, Lo Gorton, Donal Leech, Gabriele Favero

Research output: Contribution to journalArticlepeer-review

7 Citations (SciVal)

Abstract

Here the feasibility of layers based on the conducting polymer polyaniline (PANI) as component of glucose biosensors using glucose oxidase (GOx) as enzyme and [Os(bpy)(2)(4-aminomethylpyridine)Cl]PF6 (OsCmplx) as electrochemical mediator, is evaluated. Particularly, PANI was employed to obtain a nanostructured macroporous material (m-PANI) around polystyrene nanoparticles taken as template and the mediator was co-immobilized during the polymerizing procedure. The GOx biosensor based on OsCmplx modified m-PANI provides a linear response to glucose concentration in the range 5 up to 65 mM with a sensitivity of 3.54 mu A/mM/cm(2) (on a projected geometric area=0.07 cm(2)), an LOD of 0.8 mM and a good precision (%RSD <= 7, n=5); the biosensor is stable showing a decrease of 10% to the value of the sensitivity after 15 days of use and of about 50% after 40 days.
Original languageEnglish
Pages (from-to)1623-1630
JournalElectroanalysis
Volume26
Issue number7
DOIs
Publication statusPublished - 2014

Subject classification (UKÄ)

  • Biological Sciences

Keywords

  • Polyaniline
  • Macroporous material
  • Osmium redox complex
  • Glucose
  • biosensor

Fingerprint

Dive into the research topics of 'Composite Material Based on Macroporous Polyaniline and Osmium Redox Complex for Biosensor Development'. Together they form a unique fingerprint.

Cite this