Concomitant therapy: an outcome variable for musculoskeletal disorders? Part 2: total joint replacement in osteoarthritis trials

Jean-Francis Maillefert; Gillian A Hawker; Laure Gossec; Nizar N Mahomed; Stefan Lohmander; Paul A Dieppe; Gustavo Zanoli; Marc C Hochberg; Maxime Dougados

Concomitant therapy: an outcome variable for musculoskeletal disorders? Part 2: total joint replacement in osteoarthritis trials

Jean-Francis Maillefert, Gillian A Hawker, Laure Gossec, Nizar N Mahomed, Stefan Lohmander, Paul A Dieppe, Gustavo Zanoli, Marc C Hochberg, Maxime Dougados

Orthopaedics (Lund)

Research output: Contribution to journal › Article › peer-review

Abstract

Interest has grown in using the requirement of total joint replacement (TJR) as a "hard" outcome measure. Limitations exist, however, in the use of such an outcome, in particular the variability in the decision to perform surgery, length of surgical waiting lists, and sensitivity to change. This special interest group is exploring ways of retaining the clinical relevance of TJR but overcoming the problems--2 alternative outcomes are being considered: "time to physician's decision to recommend surgery" and "time to fulfilling criteria for total joint replacement."

Original language	English
Pages (from-to)	2449-51
Number of pages	3
Journal	Journal of Rheumatology
Volume	32
Issue number	12
Publication status	Published - 2005 Dec

Subject classification (UKÄ)

Rheumatology and Autoimmunity

Free keywords

Arthroplasty, Replacement
Humans
Musculoskeletal Diseases
Osteoarthritis
Outcome Assessment (Health Care)
Randomized Controlled Trials as Topic
Salvage Therapy
Treatment Failure

Cite this

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title = "Concomitant therapy: an outcome variable for musculoskeletal disorders? Part 2: total joint replacement in osteoarthritis trials",

abstract = "Interest has grown in using the requirement of total joint replacement (TJR) as a {"}hard{"} outcome measure. Limitations exist, however, in the use of such an outcome, in particular the variability in the decision to perform surgery, length of surgical waiting lists, and sensitivity to change. This special interest group is exploring ways of retaining the clinical relevance of TJR but overcoming the problems--2 alternative outcomes are being considered: {"}time to physician's decision to recommend surgery{"} and {"}time to fulfilling criteria for total joint replacement.{"}",

keywords = "Arthroplasty, Replacement, Humans, Musculoskeletal Diseases, Osteoarthritis, Outcome Assessment (Health Care), Randomized Controlled Trials as Topic, Salvage Therapy, Treatment Failure",

author = "Jean-Francis Maillefert and Hawker, {Gillian A} and Laure Gossec and Mahomed, {Nizar N} and Stefan Lohmander and Dieppe, {Paul A} and Gustavo Zanoli and Hochberg, {Marc C} and Maxime Dougados",

year = "2005",

month = dec,

language = "English",

volume = "32",

pages = "2449--51",

journal = "Journal of Rheumatology",

issn = "0315-162X",

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TY - JOUR

T1 - Concomitant therapy

T2 - an outcome variable for musculoskeletal disorders? Part 2: total joint replacement in osteoarthritis trials

AU - Maillefert, Jean-Francis

AU - Hawker, Gillian A

AU - Gossec, Laure

AU - Mahomed, Nizar N

AU - Lohmander, Stefan

AU - Dieppe, Paul A

AU - Zanoli, Gustavo

AU - Hochberg, Marc C

AU - Dougados, Maxime

PY - 2005/12

Y1 - 2005/12

N2 - Interest has grown in using the requirement of total joint replacement (TJR) as a "hard" outcome measure. Limitations exist, however, in the use of such an outcome, in particular the variability in the decision to perform surgery, length of surgical waiting lists, and sensitivity to change. This special interest group is exploring ways of retaining the clinical relevance of TJR but overcoming the problems--2 alternative outcomes are being considered: "time to physician's decision to recommend surgery" and "time to fulfilling criteria for total joint replacement."

AB - Interest has grown in using the requirement of total joint replacement (TJR) as a "hard" outcome measure. Limitations exist, however, in the use of such an outcome, in particular the variability in the decision to perform surgery, length of surgical waiting lists, and sensitivity to change. This special interest group is exploring ways of retaining the clinical relevance of TJR but overcoming the problems--2 alternative outcomes are being considered: "time to physician's decision to recommend surgery" and "time to fulfilling criteria for total joint replacement."

KW - Arthroplasty, Replacement

KW - Humans

KW - Musculoskeletal Diseases

KW - Osteoarthritis

KW - Outcome Assessment (Health Care)

KW - Randomized Controlled Trials as Topic

KW - Salvage Therapy

KW - Treatment Failure

M3 - Article

C2 - 16331784

SN - 0315-162X

VL - 32

SP - 2449

EP - 2451

JO - Journal of Rheumatology

JF - Journal of Rheumatology

IS - 12

ER -

Concomitant therapy: an outcome variable for musculoskeletal disorders? Part 2: total joint replacement in osteoarthritis trials

Abstract

Subject classification (UKÄ)

Free keywords

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