Conversion of acetaminophen to the bioactive N-acyl phenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system.

Edward Högestätt; Bo A Jönsson; Anna Ermund; David Andersson; Henrik Björk; Jessica P Alexander; Benjamin F Cravatt; Allan I Basbaum; Peter Zygmunt

doi:10.1074/jbc.M501489200

Conversion of acetaminophen to the bioactive N-acyl phenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system.

Edward Högestätt, Bo A Jönsson, Anna Ermund, David Andersson, Henrik Björk, Jessica P Alexander, Benjamin F Cravatt, Allan I Basbaum, Peter Zygmunt

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	31405-31412
Journal	Journal of Biological Chemistry
Volume	280
Issue number	36
DOIs	https://doi.org/10.1074/jbc.M501489200
Publication status	Published - 2005

Subject classification (UKÄ)

Medicinal Chemistry
Pharmacology and Toxicology
Occupational Health and Environmental Health

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10.1074/jbc.M501489200

1 Doctoral Thesis (compilation)

Bioactive Lipids in Nociception
Ermund, A., 2008, Clinical Chemistry and Pharmacology, Dept of Laboratory Medicine. 153 p.
Research output: Thesis › Doctoral Thesis (compilation)

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Högestätt, E., Jönsson, B. A., Ermund, A., Andersson, D., Björk, H., Alexander, J. P., Cravatt, B. F., Basbaum, A. I., & Zygmunt, P. (2005). Conversion of acetaminophen to the bioactive N-acyl phenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system. Journal of Biological Chemistry, 280(36), 31405-31412. https://doi.org/10.1074/jbc.M501489200

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title = "Conversion of acetaminophen to the bioactive N-acyl phenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system.",

author = "Edward H{\"o}gest{\"a}tt and J{\"o}nsson, {Bo A} and Anna Ermund and David Andersson and Henrik Bj{\"o}rk and Alexander, {Jessica P} and Cravatt, {Benjamin F} and Basbaum, {Allan I} and Peter Zygmunt",

year = "2005",

doi = "10.1074/jbc.M501489200",

language = "English",

volume = "280",

pages = "31405--31412",

journal = "Journal of Biological Chemistry",

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publisher = "American Society for Biochemistry and Molecular Biology",

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Högestätt, E, Jönsson, BA, Ermund, A, Andersson, D, Björk, H, Alexander, JP, Cravatt, BF, Basbaum, AI & Zygmunt, P 2005, 'Conversion of acetaminophen to the bioactive N-acyl phenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system.', Journal of Biological Chemistry, vol. 280, no. 36, pp. 31405-31412. https://doi.org/10.1074/jbc.M501489200

TY - JOUR

T1 - Conversion of acetaminophen to the bioactive N-acyl phenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system.

AU - Högestätt, Edward

AU - Jönsson, Bo A

AU - Ermund, Anna

AU - Andersson, David

AU - Björk, Henrik

AU - Alexander, Jessica P

AU - Cravatt, Benjamin F

AU - Basbaum, Allan I

AU - Zygmunt, Peter

PY - 2005

Y1 - 2005

U2 - 10.1074/jbc.M501489200

DO - 10.1074/jbc.M501489200

M3 - Article

C2 - 15987694

SN - 1083-351X

VL - 280

SP - 31405

EP - 31412

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

IS - 36

ER -

Conversion of acetaminophen to the bioactive N-acyl phenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system.

Subject classification (UKÄ)

Access to Document

Research output

Bioactive Lipids in Nociception

Cite this