Critical appraisal of the International Prophylaxis Study Group magnetic resonance image scale for evaluating haemophilic arthropathy

Mirkamal Tolend, Haris Majeed, Magdy Soliman, Paulo Daruge, Marcelo Bordalo-Rodrigues, Sergio San Juan Dertkigil, Sridhar Gibikote, Shyamkumar N. Keshava, Jennifer Stimec, Amy Dunn, Ying Jia Li, Victor Blanchette, Björn Lundin, Andrea S. Doria

Research output: Contribution to journalArticlepeer-review

Abstract

A goal of the International Prophylaxis Study Group (IPSG) is to provide an accurate instrument to measure MRI-based disease severity of haemophilic arthropathy at various time points, so that longitudinal changes in disease severity can be identified to support decisions on treatment management. We review and discuss in this paper the evaluative purpose of the IPSG MRI scale in relation to its development and validation processes so far. We also critically appraise the validity, reliability and responsiveness of using the IPSG MRI scale in different clinical and research settings, and whenever applicable, compare these clinimetric properties of the IPSG MRI scale with those of its precursors, the compatible additive and progressive MRI scales.

Original languageEnglish
Pages (from-to)565-574
Number of pages10
JournalHaemophilia
Volume26
Issue number4
Early online date2020
DOIs
Publication statusPublished - 2020 Jul

Subject classification (UKÄ)

  • Medical Imaging

Free keywords

  • children
  • hemophilic arthropathy
  • International Prophylaxis Study Group
  • joints
  • magnetic resonance imaging
  • responsiveness
  • validity

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